BACKGROUND Fasciola hepatica and F. gigantica are the causative agents of fasciolosis in domestic animals and humans. Based on the morphometric criteria, differential diagnosis between them is problematic. In addition, intermediate forms of Fasciola have been found in Iran, which makes the differentiation more difficult. The aim of the present study was to provide molecular evidence for the exi...

Here we report a rare case of living Fasciola hepatica in biliary tract. The patient was in acute phase of infection and treated successfully with 10 mg/kg oral triclabendazole after the fluke was extracted using endoscopic retrograde cholangiopancreatography (ERCP).

A study of 53 patients with eosinophilia of suspected parasitic origin was conducted. Investigations done for each case included, stool and urine examinations, absolute eosinophilic count and countercurrent immunoelectrophoresis (CIEP) using crude antigens of Fasciola hepatica, Schistosoma mansoni worms, Trichinella spiralis and Toxocara canis larvae, and hydatid fluid. Stool examination reveal...

Bovine tuberculosis (bTB) and fasciolosis are important but neglected diseases that result in chronic infections in cattle. However, in Zambia, these diseases are mainly diagnosed at abattoirs during routine meat inspection. Albeit the coinfection status, these diseases have been reported as nothing more than normal separate findings without an explanatory phenomena. Forthwith, we formulated th...

11-23 ABSTRACT A complementary DNA (cDNA) library was constructed from the mRNA of adult worms of Fasciola hepatica in the expression vector λgt11, the size of the library contained approximately 2.4 x 10 recombinants and the recombinant efficiency was 85%. The library was directedly screened with a rabbit antisera raised against a excretory-secretory (ES) antigen of Fasciola hepatica. Two posi...

Understanding genetic structure and status of genetic variation of the Fasciola gigantica and F. hepatica isolates from different hosts, has important implications for epidemiology and effective control of fasciolosis. The aim of the present work was to study the molecular characterization of Fasciola gigantica and F. hepatica isolates collected from cows and sheep, using the random amplified p...

BACKGROUND In this study, we evaluated the biochemical, immunological, histopathological and antischistosomal activities of Schistosoma mansoni or Fasciola gigantica worm homogenates mixed either with or without saponin that was extracted from Atriplex nummularia. METHODOLOGY The immunization schedule was based on subcutaneous administration of two doses (50 microg /100 microl PBS) of each ho...

A case of ectopic fascioliasis due to migration of an immature Fasciola hepatica fluke is described in a 23 year old woman from western Iran.