100 _ Important reductions in cardiovascular mortality that have occurred over the past three decades in most industrialised regions have not been accompanied by a decline in mortality or admissions to hospital for cardiac failure. ' Congestive heart failure (CHF) continues to be a lethal end stage of cardiovascular disease caused by hypertension, coronary disease, valve deformity, diabetes, an...

A cardiac contractility modulation device is a new treatment used in patients with heart failure. CCM therapy associated an increase physical activity tolerance, improved quality of life, reduced hospitalizations due to failure, and reverse remodeling the left ventricle systolic In this case, clinical benefit patient chronic atrial fibrillation postinfarction aneurysm was reported. Development ...

Mouse models mimicking human diseases are important tools in trying to understand the underlying mechanisms of many disease states. Several surgical models have been described that mimic human myocardial infarction (MI) and pressure-overload-induced cardiac hypertrophy. However, there are very few detailed descriptions for performing these surgical techniques in mice. Consequently, the number o...

Cardiac catheters allow clinicians to minimally invasively interact with the beating heart without stopping the heart or opening the chest. However, the fast motion of the intracardiac structures makes it difficult to modify and repair the tissue in a controlled and safe manner. To enable surgical procedures on the inside of the beating heart, we have developed an ultrasound-guided catheter sys...

It is sensible to use paracetamol to reduce the discomfort caused by minor acute infections, surgical procedures and triple antigen. It is also sensible to use paracetamol to reduce fever in patients with cardiac or respiratory failure. However, there is little evidence to support the use of paracetamol to treat fever in patients without heart or lung disease, or to prevent febrile convulsions....

BACKGROUND AND AIM OF THE STUDY Implications of Cardiac troponin (cTnI) release after cardiac transplantation are still unclear. This study disclosed risk factors and prognostic implication of cTnI early levels in a single centre cohort operated on between January 1999 and December 2010. METHODS Data on 362 consecutive recipients (mean age: 47.8±13.7, 20.2% female, 18.2% diabetics, 22.1% with...

Surgical procedures guided by non-optical imaging represent a growing proportion of medical interventions. The goal of this type of approach is to reduce the invasiveness of current procedures or to treat disease using new procedures which would not possible without the assistance of medical imaging. The field of cardiac surgery represents a medical subspecialty where image-guided interventions...

Symptomatic paravalvular leak (PVL) complicates up to 12 % of surgical valve replacements. When patients present with congestive heart failure and/or haemolysis, reoperation for repeat valve replacement may be undertaken, but presents greater risk and lower likelihood of success than the initial operation. Therefore, percutaneous approaches to PVL closure have been developed by specialists in s...

Kawasaki disease is an acute inflammatory disorder of medium-sized arteries that predominantly affects cardiac coronary arteries and children under the age of 5 years. Cardiac involvement usually happens later than 10 days after the onset of illness. Most of cardiac complications are coronary artery abnormalities (ectasia or aneurysms) and subclinical myocarditis. Clinical myocarditis (symptoma...

BACKGROUND Lack of data exists on the surgical management of adult congenital heart disease on the African continent. This study was undertaken to describe the clinical profile and surgical outcome of adult patients with congenital heart disease undergoing surgery in a single-center African study population. METHODS A retrospective medical chart review of consecutive adult patients (≥18 years...