نتایج جستجو برای: factor v inhibitor
تعداد نتایج: 1288426 فیلتر نتایج به سال:
Tissue factor (TF) pathway inhibitor (TFPI) is an anticoagulant protein that inhibits early phases of the procoagulant response. Alternatively spliced isoforms of TFPI are differentially expressed by endothelial cells and human platelets and plasma. The TFPIβ isoform localizes to the endothelium surface where it is a potent inhibitor of TF-factor VIIa complexes that initiate blood coagulation. ...
A new case of combined factor V-VIII deficiency is reported with in vitro studies of factors V and VIII activation by thrombin. The normal activation of factors V and VIII demonstrated in the patient's plasma and the equivalent levels of factor VIII coagulant activity and coagulant antigen support the hypothesis that a quantitative rather than qualitative defect in factors V and VIII is present...
The aim of this study was to identify hereditary and acquired risk-factors as they are related to the occurrence of stroke in children. We identified 21 children with stroke. A search of the Factor V Leiden mutation, the Factor II G20210A variant, and the thermolabile variant of methylenetetrahydrofolate reductase was performed in patients and in a control group (n = 115). We identified risk fa...
Native bovine factor V exists in three forms of differing molecular size, the oligomeric interconvertible forms A and C and a phospholipid-containing complex designated form L. Thrombin increases the activity of form A to a greater extent than form L and does not alter the activity of form C. Thrombin-activated form A and form C function as potent inhibitors of thrombin activation of form A but...
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