Abstract: Introduction: The purpose of the present study was to design, develop, and characterize transdermal patches containing Simvastatin for management blood lipid levels. Materials Methods: Transdermal were prepared by solvent casting method. evaluated physicochemical characteristics such as thickness, weight variation, folding endurance, percentage moisture uptake, content, drug ex-vivo p...

Most basaltic explosive eruptions intensify abruptly, allowing little time to document processes at the start of eruption. One opportunity came with initiation activity from fissure 8 (F8) during 2018 eruption on lower East Rift Zone K?lauea, Hawaii. F8 erupted in four episodes. We recorded 28 min high-definition video a 51-min period, capturing onset second episode 5 May. From videos, we were ...

Cytogenetic re-evaluation of a fibroblast cell line from a female Hunter's syndrome case with a balanced X;autosome translocation, which had previously been reported to have a breakpoint in Xq26 to Xq27, showed the breakpoint to be either between Xq27 and Xq28 or within Xq28. The normal X chromosome was preferentially inactivated, supporting the view that the translocation had disrupted the Hun...

Abstract Lack of clinically validated markers associated with the development neutralizing antibodies (inhibitors) to replacement protein-drug, Factor VIII (FVIII) is a major challenge in managing Hemophilia A (HA). By utilizing Machine Learning (ML) and Explainable AI (XAI) we identified ranked relevant variables (biomarkers) that could be predictive for developing inhibitors FVIII drugs hemop...

Bu çalışma, Çukurova Üniversitesi, Ziraat Fakültesi araştırma alanında, 2019 ve 2020 yılı üretim sezonunda ana ürün koşullarında yapılmıştır. Araştırmaya konu olan denemeler tesadüf bloklar deneme desenine göre, üç tekrarlamalı olarak kurulmuştur. Araştırmada, farklı yer fıstığı çeşitlerinin melezlemesinden elde edilen pedigri seleksiyon yöntemine göre seçilen denemeye değer bulunan 14 adet ile...