Mục tiêu: Nghiên cứu vai trò các đa hình đơn gen huyết khối với nguy cơ sẩy thai tái diễn. Đối tượng và phương pháp nghiên cứu: mô tả cắt ngang có đối chứng trên 200 phụ nữ tiền sử liên tiếp 100 đã từng con sinh đẻ bình thường tại bộ môn Sinh học Di truyền y học, Học viện Quân Y. Kết quả: Đa -675 4G/5G của SERPINE1 gặp nhiều nhất tỷ lệ 81,5% ở nhóm thai, phổ biến thứ hai là FGB: -455 G>A(chi...

Pronounced electron–phonon coupling is observed for the F7/2↔F5/2 4 f transitions of Yb doped into CsCdBr3. A comparison of the Raman spectrum and the luminescence excitation sideband accompanying the F7/2(0)→F5/2(28) crystal-field transition reveals vibrational properties of the @YbBr6# coordination unit that differ markedly from those of the CsCdBr3 host. In particular, the vibronic transitio...

Giardiasis, a gastrointestinal disease caused by Giardia duodenalis, is currently treated mainly with nitroimidazoles, primarily metronidazole (MTZ). Treatment failure rates of up to 20 percent reflect the compelling need for alternative treatment options. Here, we investigated whether orlistat, a drug approved to treat obesity, represents a potential therapeutic agent against giardiasis. We co...

Although 24 Alzheimer's disease (AD) risk loci have been reliably identified, a large portion of the predicted heritability for AD remains unexplained. It is expected that additional loci of small effect will be identified with an increased sample size. However, the cost of a significant increase in Case-Control sample size is prohibitive. The current study tests whether exploring the genetic b...

As thrombin is proposed to be involved in stimulating myometrial contractility during labor and preterm labor, we aimed to investigate the expression of prothrombin (F7), the precursor of thrombin, its receptors, the protease-activated receptor (PAR) family (F2R, F2RL1, F2RL2, and F2RL3), and prothrombinase FGL2 in human myometrium during pregnancy and labor. Messenger RNA and protein were isol...

Monoclonal antibody (MAb) F7-26 generated against nitrogen mustard (HN2)-treated DNA (O.S. Frankfurt, Exp. Cell Res., 170: 369-380, 1987) reacted with regions of local DNA denaturation (distortion) induced by DNA alkylation. The relationship between immunoreactivity of cellular DNA with MAb F7-26 and cytotoxic effects of HN2, L-phenylalanine mustard (L-PAM), and 1,3-bis(2-chloroethyl)-1-nitroso...

In unpublished work, Geelen proved that a matroid is nearregular if and only if it has no minor isomorphic to U2,5, U3,5, F7, F ∗ 7 , F− 7 , (F − 7 ) ∗, AG(2, 3)\e, (AG(2, 3)\e)∗, ∆T (AG(2, 3)\e), or P8. We provide a proof of this characterization.

We show that the excluded minors for the class of matroids that are binary or ternary are U2,5, U3,5, U2,4⊕F7, U2,4⊕F ∗ 7 , U2,4⊕2F7, U2,4 ⊕2 F ∗ 7 , and the unique matroids obtained by relaxing a circuithyperplane in either AG(3, 2) or T12. The proof makes essential use of results obtained by Truemper on the structure of almost-regular matroids.