Human adenoviral serotype 5 (HAdV-5) vectors have predominantly hepatic tropism when delivered intravascularly, resulting in immune activation and toxicity. Coagulation factor X (FX) binding to HAdV-5 mediates liver transduction and provides protection from virion neutralization in mice. FX is dispensable for liver transduction in mice lacking IgM antibodies or complement, suggesting that alter...

The amateur astronomy community has a long tradition of performing routine visual observations of the planets with small telescopes, but in the last decade, CCD imaging has largely replaced visual observing as the primary method of recording planetary detail. Low cost 24bit color CCD video conferencing cameras (webcams) coupled to amateur telescopes (typically 0.2-0.3m aperture) have become pow...

The Hushpuckney Shale Member of the Swope Formation (Missourian Stage, eastern Kansas) is the core shale of a Kansastype cyclothem, formed during the late transgressive to early regressive phases of a Late Pennsylvanian glacio-eustatic cycle. Coeval high-frequency climato-environmental dynamics of the Midcontinent Seaway are preserved in the KGS Orville Edmonds No. 1A study core as centimeter-s...

This paper focuses on the factors which influence collaborative learning in distance education. Distance education has been around for many years and the use of collaborative learning techniques in distance education is becoming increasingly popular. Several studies have demonstrated the superiority of collaborative learning over traditional modes of learning and it has been identified as a pot...

Several theories have been proposed regarding how causal relations among features of objects affect how those objects are classified. The assumptions of these theories were tested in three experiments which manipulated the causal knowledge associated with novel categories. There were three results. The first was a multiple cause effect in which a feature’s importance increases with its number o...