We examined the effect of lactational exposure to tributyltin on innate immunodefenses in the F1 generation using in vivo and in vitro experiments. Pregnant C57BL/6 mice were given drinking water containing 0, 15, or 50 microg/ml of tributyltin chloride (TBTCl) from parturition to weaning. At weaning time, offspring were inoculated with Escherichia coli K-12, and bacterial clearances from the p...

1. The activity of the soluble phosphokinase for histone F1 increases in regenerating rat liver during the first period of DNA synthesis after partial hepatectomy. The increase probably represents new enzyme synthesis. 2. A dose of 500rd of gamma-irradiation given early in G1 decreases the amount of histone F1 phosphokinase found 22h after partial hepatectomy by 60-70%. 3. The enzyme preparatio...

Purified preparations of F1-ATPase (ATP phosphohydrolase; EC 3.6.1.3) isolated from yeast mitochondria catalyze the reaction of oleoylphosphate with ADP to yield ATP and oleic acid. Formation of ATP is specifically inhibited by the F1-ATPase inhibitor 1799 and by dinitrophenol. In the presence of F1, dinitrophenol "uncouples" the synthase reaction by causing rapid hydrolysis of oleoylphosphate ...

In classical fixed point and coincidence theory, the notion of Nielsen numbers has proved to be extremely fruitful. Here we extend it to pairs ( f1, f2) of maps between manifolds of arbitrary dimensions. This leads to estimates of the minimum numbers MCC( f1, f2) (and MC( f1, f2), resp.) of path components (and of points, resp.) in the coincidence sets of those pairs of maps which are ( f1, f2)...

For simplicity, we adopt the following rules: x denotes a set, n, m, k denote natural numbers, r denotes a real number, V denotes a real linear space, v, w denote vectors of V , A1 denotes a finite subset of V , and A2 denotes a finite affinely independent subset of V . One can prove the following propositions: (1) For all real-valued finite sequences f1, f2 and for every real number r holds (I...

Changes in DNA methylation may play a role in the genetic mechanism underlying glucose intolerance in the offspring of mothers with diabetes. Here, we established a rat model of moderate intrauterine hyperglycemia induced by streptozotocin to detect glucose and lipid metabolism of first-generation (F1) and second-generation (F2) offspring. Moderate intrauterine hyperglycemia induced high body w...

In classical fixed point and coincidence theory the notion of Nielsen numbers has proved to be extremely fruitful. Here we extend it to pairs (f1, f2) of maps between manifolds of arbitrary dimensions. This leads to estimates of the minimum numbers MCC(f1, f2) (and MC(f1, f2), resp.) of pathcomponents (and of points, resp.) in the coincidence sets of those pairs of maps which are homotopic to (...

Male (NZW x BXSB) F1 (W/B F1) mice, which develop lupus nephritis, myocardial infarction, and thrombocytopenia, showed reduced platelet lifespan (PLS) and increased platelet-associated antibody (PAA) values. There were statistically significant correlations between the increase in PAA values and either the reduction in PLS or the decrease in platelet counts. This and the results of platelet tra...

In this paper we deal with a particular class of rank two vector bundles (\emph{instanton} bundles) on the Fano threefold index one $F:=\mathbb{F}_1 \times \mathbb{P}^1$. We show that every instanton bundle $F$ can be described as cohomology monad whose terms are free sheaves. Furthermore prove existence for any admissible second Chern and construct nice component moduli space where they sit. F...