Atypical chronic myeloid leukemia, BCR-ABL1 negative (aCML) is a rare myelodysplastic syndrome (MDS)/myeloproliferative neoplasm (MPN) for which no current standard of care exists. The challenges of aCML relate to its heterogeneous clinical and genetic features, high rate of transformation to acute myeloid leukemia, and historically poor survival. Therefore, allogeneic hematopoietic stem cell t...

Hemangioendothelioma is borderline or intermediate type of vascular neoplasm. Hemangioendothelioma is rare lesion that constitutes less than 0.5% of the malignant tumors of bone. We present a case of low-grade hemagioendothelioma of the skull in a 29-yr-old woman. She had pain, diplopia and exophthalmos of the left eye. Radiographic images showed a relatively well-demarcated, expansile osteolyt...

BACKGROUND Melanomas are malignant neoplasm of melanocytic origin, commonly seen on skin and various mucous membranes. Melanomas are the commonest intraocular malignant tumour in the adults. CASE PRESENTATION A 50-year-old female presented with complains of painless progressive swelling in right cheek region of two months duration. Examination revealed a 6 x 4 cm bony hard swelling in right z...

abstract gastric cancer is one of the most common and most fatal neoplasms in human. its skeletal metastasis is less frequent, particularly when solitary. the objective of this article is to represent a case of solitary fibular metastasis from this cancer not reported before based on medline search.

objectives we undertook this study to compare the results of hormone receptor assessment in cnb and surgical samples on our patients. patients and methods hormone receptor status was determined in cnb and surgical samples in breast cancer patients whose cnb and operation had been performed in this institute from 2009 to 2011 and had not undergone neoadjuvant chemotherapy. results about 350 pati...

background: information regarding solid pseudopapillary neoplasm (spn) of the pancreas is limited in iran. we aimed to review the clinicocytopathological features and follow-up of patients with spn of pancreas who were diagnosed in a single center in iran. methods: seven patients with spn of the pancreas were diagnosed during january 2010 to march 2015 at the digestive disease research institut...