Sir, Cavernous angioma (CA) of central nervous system (CNS) is an uncommon disease and presents with seizures, hemorrhagic episodes, and rarely with focal deficits.[1] Multiple CAs are often familial. Giant CAs (GCAs) are extremely rare and multiple GCAs are sill rarer. Sometimes, these lesions can be fatal from massive hemorrhage. Most GCAs present as multicystic lesions with hemosiderin ring ...

Apocrine hidrocystoma is a benign cystic tumour. The head and neck region is the site of predilection; occurrence in the scalp is extremely rare. We report a rare case of giant apocrine hidrocystoma with an unusual presentation as scalp haematoma.

Omental lipomas are extremely rare tumors of childhood. We report a case of solitary giant lipoma of the omentum in a child, successfully managed by complete excision, without any recurrence on follow-up study.

BACKGROUND Pericallosal aneurysms are encountered less than 6.7%, and giant aneurysms among them even less. Giant azygos pericallosal artery aneurysm at the callosomarginal bifurcation is extremely rare, and our case presented herein is the second one. The case is discussed with thorough review of the literature. METHODS A 65-year-old woman presented with an extremely rare giant aneurysm on t...

The problem of predicting the upper cut-off of the cosmic ray spectrum is re-examined. Some aspects of extremely high energy interactions and their implications for the interpretation of giant air showers are also discussed.

Doctors have no ethical obligation to provide futile treatment. This has been true since the time of Hippocrates who warned physicians not to treat patients who were "overmastered by their disease." This principle remains valid today but, as the Society for Critical Care Medicine notes, it is difficult to identify treatment as absolutely futile in all but a few clinical situations. Far more com...

Presenter: Kiarash Mashayekhi MD, MS | San Joaquin General Hospital Background: Osteoclast-like Giant Cell Tumors (OGCT) of the pancreas is extremely rare, highly aggressive tumors which are still poorly understood. To date, multiple cases have been reported characterize these as variants pancreatic giant cell and provide evidence supporting a duct epithelium origin. The current prognostic fact...