Investigation of mild, inherited increased serum alkaline phosphatase activity partially combined with Gilbert's syndrome in one family showed, apart from a normal liver fraction, an intestinal isoenzyme pattern and an extra band in the agar electrophoresis. Analysis by agarose electrophoresis before and after incubation of neuraminidase showed that the extra fraction was an intestinal variant ...

Entamoeba histolytica, a pathogenic parasite, is the causative organism of amoebiasis and uses human colon to complete its life cycle. It destroys intestinal tissue leading invasive disease. Since it does not form cyst in culture medium, reptilian parasite invadens serves as model system study encystation. Detailed investigation on mechanism formation, information ultra-structural changes wall ...

During the excavations of the XIX century Meadowlark cemetery (Manhattan, Kansas, US), samples of sediments were taken from around five skeletons, and analyzed to detect intestinal parasites. No helminth eggs were found, but immunological ELISA tests for Entamoeba histolytica were positive in three samples. The immunological techniques have been successfully used in paleoparasitology to detect ...

An adolescent female with long-standing, difficult-to-control ulcerative colitis developed leukocytoclastic vasculitis, a rare cutaneous extra-intestinal manifestation of the inflammatory bowel disease. The authors provide a literature review on leukocytoclastic vasculitis complicating ulcerative colitis. Furthermore, the clinical features of leukocytoclastic vasculitis are compared and contras...

BACKGROUND Intestinal parasitic infections (IPIs) among indigenous people have been widely documented in Malaysia, however, the prevalence of these infections remains high. In the past, most studies have focused on specific species of parasites but polyparasitism has received limited attention. In addition, epidemiology studies on indigenous people tend to consider them as a homogenous group, w...

Protozoa that parasitize the human intestine include Entamoeba histolytica, Blastocystis hominis, Trichomonas hominis, Cryptosporidium parvum, Giardia lamblia, Balantidium coli, Isospora, and other protozoa. Most intestinal protozoan infections can cause acute or chronic diarrhea in healthy individuals and may result in intractable, life-threatening illness in patients in immunosuppressive stat...

Amoebiasis caused by entamoeba histolytica mainly involves the gastrointestinal tract. Its extraintestinal involvement is mainly seen in liver and lung. Involvement of the brain is known but extremely unusual. Even rarer is involvement of the brain without any involvement of lung or liver. We present cerebral computed tomographic findings of a case with cerebral amoebiasis without any involveme...

Targeting of Wnt signaling represents a promising anti-cancer therapy. However, the consequences of systemically attenuating the Wnt pathway in an adult organism are unknown. Here, we globally prevent Wnt secretion by genetically ablating Wntless. We find that preventing Wnt signaling in the entire body causes mortality due to impaired intestinal homeostasis. This is caused by the loss of intes...

A number of protozoa are known to cause bowel disease in humans. Here the author discusses clinical features, diagnosis and management those more likely be encountered by doctors temperate zones.