A 24-year-old man with hereditary multiple exostoses had numbness of the lower extremities and difficulty walking. CT displayed a calcified extradural mass lesion within the spinal canal at T-8 causing cord compression. MR imaging showed it to be contiguous with the upper endplate of T-8, suggesting the diagnosis of osteochondroma, a rare cause of cord compression, and distinguishing the lesion...

UNLABELLED Osteochondroma, which is also known as exostosis, is the most common benign bone tumor. Although foot and hand surgeons frequently encounter the subungual exostosis, exostoses commonly localize to other areas of the skeleton as well. In this review, we describe the clinical and diagnostic imaging characteristics of benign bone tumors and, in particular, the osteochondroma and its sur...

Three cats with feline arylsulfatase-B--deficient mucopolysaccharidosis were studied by light and transmission electron microscopy. Membrane-bound cytoplasmic inclusions were present in hepatocytes, bone marrow granulocytes, vascular smooth muscle cells, and fibroblasts in skin, cornea, and cardiac valves. Central nervous system lesions were restricted to mild ventricular dilatation, perithelia...

We describe the first case of the coexistence of the hereditary connective tissue disorder multiple exostoses (HME) and an acquired connective tissue disorder manifest by the overlap of dermatomyositis (DM), scleroderma (PSS), high titre speckled pattern antinuclear antibodies, and increased antibodies to double stranded deoxyribonucleic acid (DNA). Furthermore this patient developed chondrosar...

In 1944, after a legal case of disputed paternity in Switzerland, Nievergelt reported three children with deformities like those ofthe alleged father. They had talipes with tarsal synostosis, dysplasia of the elbows with radio-ulnar synostosis and subluxation of the radial head, and dysplasia of the tibia and fibula with exostoses. So far as had been ascertained neither of the parents of the fa...

Fibrolipomatous hamartomas are rare benign nerve tumors caused by a proliferation of fibroadipose tissue within the perineurium and endoneurium peripheral nerves. They often present during first second decades life with progressive neuritic symptoms regularly associated territory overgrowth, or macrodactyly, as well development exostoses. These missed clinical exam due to lack recognition sympt...