Objective: Exopolysaccharides gained attention as new source for cancer treatment as recent treatments cause side effects and multidrug resistance. Polysaccharides containing sulfur and uronic acids exhibited antioxidant activity, by restoring cell redox regulation, thus inhibiting cell proliferation and cancer formation. Following this context, our study was performed to assess the cytotoxic a...

The use of microbial exopolysaccharides (EPS) in the food, pharmaceutical, and chemical industries has steadily increased during the past decade. A bioactive EPS producing microorganism, Streptomyces nasri was isolated from Kuwait tropical soil and the proteopolysaccharide was tested for its antimicrobial activity. The isolate was subjected to ultraviolet (UV) radiation and acridine orange (AO)...

Exopolysaccharides have a diverse set of functions in most bacteria including a mechanistic role in protecting bacteria against environmental stresses. Among the many functions attributed to the exopolysaccharides, biofilm formation, antibiotic resistance, immune evasion and colonization have been studied most extensively. The exopolysaccharide produced by many Gram positive as well as Gram neg...

The lactic acid bacteria Lactococcus lactis and Streptococcus thermophilus play a crucial role in the manufacture of dairy products such as cheese, buttermilk and yogurt. In this contribution, different metabolic engineering strategies are described aimed at improvement of the quality of the fermented dairy product. By increased production of diacetyl or acetaldehyde, the particular flavour of ...

Bacterial EPSs (exopolysaccharides) are believed to play an important role in the environment by promoting survival strategies such as bacterial attachment to surfaces and nutrient trapping, which facilitate processes of biofilm formation and development. These microbial biofilms have been implicated in corrosion of metals, bacterial attachment to prosthetic devices, fouling of heat exchange su...

Dental unit waterlines are heavily colonized by bacteria which contaminate the water used to perform intraoral, and sometimes invasive, procedures. There is little information on the nature of the biofilm colonizing the flexible plastic tubing used to supply water to the different handpieces. We have therefore undertaken quantitative microbial analysis and ultrastructural studies of these biofi...