BACKGROUND Clinical significance of delayed-onset neutropenia (DON) after autologous hematopoietic stem-cell transplantation (ASCT) has not been well described. We conducted a retrospective cohort study to examine risk factors and clinical impact of DON. DESIGN AND METHODS Subjects were consecutive 108 patients with B-cell lymphoma receiving ASCT. We defined DON as absolute neutrophil counts ...

Mycotoxins are secondary metabolites of fungi that grow on a variety of grains, feedstuffs and animal feed. Feed containing moderate to high levels of mycotoxins cause clinical symptoms in most animals, ranging from organ damage to acute mortality. Consumption of low levels of contaminated feed may result in subclinical problems such as immunosuppression. More than 500 mycotoxins have been iden...

A total of 226 samples of maize and 59 of wheat from the 2004-2007 harvests were investigated for the presence and concentration of deoxynivalenol (DON). Samples of the 2004 harvest were analyzed after their storing for one year in barns, while those of the 2005-2007 harvest were taken directly off fields immediately after the harvest. The samples were analyzed by liquid chromatography on an OD...

Jury nullification, defined as occurring when a jury acquits “in the teeth of both law and facts,”1 has stimulated both enthusiastic praise2 and harsh condemnation.3 Although there is no clear account or tabulation of how often juries nullify, the effect when a jury nullifies is unambiguous: it ends the case. A court, even if convinced that the jury ignored or misinterpreted the facts or the la...

BACKGROUND Deoxynivalenol (DON) is a toxic fungal metabolite that frequently contaminates cereal crops. DON is toxic to animals, but the effects on humans are poorly understood, in part because exposure estimates are of limited precision. OBJECTIVES In this study we used the U.K. adult National Diet and Nutrition Survey to compare 24-hr urinary DON excretion with cereal intake. METHODS One ...

A feeding trial was conducted to evaluate the effects of diets contaminated with deoxynivalenol (DON on the performance of broilers and on the electro-physiological parameters of the gut. The control group was fed the starter and finisher diets without addition of DON. Another group of broilers was fed the starter and finisher diets with 10 mg/kg DON, whereas another group was fed the DON-conta...

AbstractThe occurrence of deoxynivalenol (DON) in retail foods in Tehran (Iran) was determined using high-performance liquid chromatography technique and immunoaffinity column as the clean-up step. A method was validated for analysis of DON in rice, bread, puffed corn snack and wheat flour. The average recoveries and precision (RSD) for DON in different foods ranged 84.2-93.1% and 2.9-12.0%, re...