Microleakage is related to recurrent decay, inflammation of vital pulps, and reinfection of previously treated root canals. The purpose of this investigation was to compare the abilities of new adhesive cements and conventional nonadhesive controls to prevent microleakage under stainless steel crowns on primary anterior teeth. Standardized preparations were made, and stainless steel crowns were...

The anesthetic effects of clove-oil-derived eugenol were studied in the zebrafish, Danio rerio (Hamilton). Acute lethality and the effects of exposures to various dosages of eugenol were measured. The estimated 96-h LC50 for eugenol was 21 ppm. Times to induction and recovery from anesthesia were measured and compared with MS-222 under similar conditions. Eugenol induced anesthesia faster and a...

The objective of this research was to evaluate, in vitro, the importance of the correct manipulation of endodontic sealers, correlating it with flow rate and with the consequent obturation of root canals. Twenty-four human canines were prepared, 1 mm from the apex, with K-files up to size 50, by means of the step-back technique. Six lateral canals were then drilled in each tooth, with size 10 f...

Eugenol and carvacrol from clove and oregano, respectively, are agonists of the warmth-sensitive transient receptor potential channel TRPV3 and the irritant-sensitive transient receptor potential ankyrin (TRPA)-1. Eugenol and carvacrol induce oral irritation that rapidly desensitizes, accompanied by brief enhancement of innocuous warmth and heat pain in humans. We presently investigated if euge...

UNLABELLED Eugenol, a natural capsaicin congener, is widely used in dentistry. Eugenol inhibits voltage-activated Na(+) and Ca(2+) channels in a transient receptor potential vanilloid 1 (TRPV1)-independent manner. We hypothesized that eugenol also inhibits voltage-gated K(+) currents, and investigated this in rat trigeminal ganglion neurons and in a heterologous system using whole-cell patch cl...

The success rate of the given fixed partial denture and longevity is depend on tooth preparation usage luting cement under prosthesis. Luting plays an important role in maintaining or securing prosthesis cemented position. should be bio compatible, it non-irritating to underlying structure pulp, maintain adequate marginal seal. In recent days so many newer cements has been introduced dentistry,...

In cardiac and skeletal muscle, eugenol (μM range) blocks excitation-contraction coupling. In skeletal muscle, however, larger doses of eugenol (mM range) induce calcium release from the sarcoplasmic reticulum. The effects of eugenol are therefore dependent on its concentration. In this study, we evaluated the effects of eugenol on the contractility of isolated, quiescent atrial trabeculae from...

The aim of this study was to investigate the antibacterial activity of pulp capping materials used in primary teeth (formocresol [FC], zinc oxide and eugenol cement [ZOE], ZOE mixed with FC [ZOEFC], mineral trioxide aggregate [MTA] and calcium hydroxide [CH]) against cariogenic bacteria. The agar plate diffusion test was used for the cultures, including saline solution as a negative control. A ...

Eugenol has been widely used in dental practice to relieve pain arising from a variety of sources. Several beneficial effects of eugenol such as its anti-inflammatory, antioxidant, anesthetic and vascular and muscle relaxant activity are recognized. It seems that there is no scientific study about eugenol effects on wound healing. The present study involved the clinical anesthetic effects of di...

The effect of essential oils, eugenol, thymol and menthol, on erythrocytes, hepatocytes, dipalmitoyl phosphatidylcholine (DPPC)-liposomes and surface tension were studied at various concentrations. Maximal inhibition of eugenol, thymol and menthol on the hypotonic hemolysis in rat erythrocytes were observed at a concentration of 2 mM, 1 mM and 1 mM, respectively. Eugenol at 4 mM and thymol at 2...