Purpose: To evaluate the anticonvulsant, antimicrobial and cytotoxic activities of Berberis calliobotrys. Methods: The powdered plant material (10 kg) was extracted thrice with methanol (3 × 12 L) by dipping for seven days. The methanol extract was concentrated to dryness under reduced pressure, and then successively fractionated with solvents of different polarity, including n-hexane, chlorofo...

In Kenya, leaves and roots from Croton macrostachyus are used as a traditional medicine for infectious diseases such as typhoid and measles, but reports on possible antimicrobial activity of stem bark do not exist. In this study, the antibacterial and antifungal effects of methanol, ethyl acetate and butanol extracts, and purified lupeol of C. macrostachyus stem bark were determined against imp...

Bidens pilosa is a plant used by Amazonian and Asian folks for some hepatopathies. The hydroethanol crude extract and three fractions were assessed for antioxidant and hepatoprotective effects. Higher levels of scavenger activity on the 1,1-diphenyl-2-picrylhydrazyl radical, inhibition of deoxyribose oxidation and lipid peroxidation in vitro were detected for the ethyl acetate fraction (IC(50)~...

The methanol and fractionated extracts (hexane, ethyl acetate and water) of Alpinia mutica (Zingiberaceae) rhizomes were investigated for their cytotoxic effect against six human carcinoma cell lines, namely KB, MCF7, A549, Caski, HCT116, HT29 and non-human fibroblast cell line (MRC 5) using an in vitro cytotoxicity assay. The ethyl acetate extract possessed high inhibitory effect against KB, M...

Article history: Received on: 26/01/2013 Revised on: 19/02/2013 Accepted on: 04/03/2013 Available online: 30/03/2013 The present study aims to investigate the antidiabetic activity of roots of Cayratia trifolia (L.) Domin in alloxan induced diabetic rats. Phytochemical studies showed the presence of steroids, flavonoids and alkaloids in petroleum ether, ethyl acetate and ethanol extracts, respe...

BACKGROUND The aim of this study was to evaluate the antimicrobial and antioxidant activities of the methanol extract, fractions and isolated compounds from Entada abyssinica stem bark, plant used traditionally against gastrointestinal infections. METHODS The methanol extract of E. abyssinica stem bark was pre-dissolved in a mixture of methanol and water, and then partitioned between n-hexane...

aim of the study: the objective of this study was to evaluate the anti-inflammatory and analgesic activities of the hydro-alcoholic extract of the pods of astragalus hamosus (haah), a plant used in iranian traditional medicine, and antinociceptive effects of different fractions in animal models. material and methods: the anti-inflammatory effect was evaluated by the rat paw edema induced by for...

BACKGROUND The efficacy of Centella asiatica for incision and burn wounds are not fully understood. Here, we report the wound healing activities of sequential hexane, ethyl acetate, methanol, and water extracts of Centella asiatica in incision and partial-thickness burn wound models in rats. METHODS Male Sprague-Dawley rats weighing 250-300 g were randomly divided into incision and burn wound...

The antioxidant and hepatoprotective activities of ethyl acetate extract was carefully investigated by the methods of DPPH radical scavenging activity, Hydroxyl radical scavenging activity, Superoxide radical scavenging activity, Hydrogen peroxide radical scavenging activity and its Reducing power ability. All these in vitro antioxidant activities were concentration dependent which were compare...