Patients with gastroesophageal reflux may have extra-esophageal manifestations. We report a 46 years old ex-smoker woman presenting with a sensation of burning mouth, xerostomia and glossitis. The patient had a history of heartburn, dysphonia and cough. Mouth examination showed a bad hygiene and abundant accumulation of plaque. Esophageal pH measurement was abnormal. Laryngoscopy showed a poste...

OBJECTIVE To report the prevalence of esophagitis in patients with pH-documented laryngopharyngeal reflux. STUDY DESIGN Prospective study of 58 consecutive patients with documented laryngopharyngeal reflux, all of whom underwent transnasal esophagoscopy as part of their reflux evaluations. METHODS All patients with a diagnosis of laryngopharyngeal reflux confirmed by abnormal pharyngeal pH ...

BACKGROUND/AIMS Functional constipation and gastroesophageal reflux disease are two major and commonly encountered components of childhood functional gastrointestinal disorders. Epidemiological studies in the adult population support that there is a significant overlap between the different functional disorders of the digestive tract. Therefore, we aimed to investigate the frequency of gastroes...

CONTEXT In infants, it is not always easy to distinguish between pathological and physiological gastroesophageal reflux based only on clinical criteria. In Brazil, studies about gastroesophageal reflux disease in infants are few and are even rare those that used prolonged esophageal pH monitoring for its evaluation. OBJECTIVE To describe the clinical features of gastroesophageal reflux diseas...

c 2017 The Korean Society of Neurogastroenterology and Motility J Neurogastroenterol Motil, Vol. 23 No. 4 October, 2017 www.jnmjournal.org Stress exacerbates heartburn symptoms in gastroesophageal reflux disease (GERD) patients and also affects visceral sensitivity. The mechanism of visceral hypersensitivity in functional gastrointestinal disorders and functional heartburn remains unclear. Howe...

Aim. Reflux of duodenal contents can induce mucosal injury, stimulate cell proliferation, and promote tumorigenesis. We examined the expression of COX2 and p53 in rat esophageal lesions induced by duodenal content reflux. Methods. Thirty 8-week-old male Wistar rats were exposed to duodenal content esophageal reflux. All animals underwent an esophagoduodenal anastomosis (EDA) with total gastrect...

background: there is no data on the prevalence and the association of gastro esophageal reflux disease (gerd) with toxic fume inhalation. therefore, we aimed to evaluate the frequency distribution of gerd symptoms among the individuals with mild respiratory disorder due to the past history of toxic fume exposure to sulfur mustard (sm). materials and methods: in a historical cohort study, subjec...

OBJECTIVE To evaluate general health condition of children operated for esophageal atresia, including complications from gastrointestinal tract and skeletal defects. METHODS Between 1990 and 2005, 77 patients were operated for esophageal atresia in the Polish Mothers Health Memorial Hospital. The study was based on retrospective analysis of medical case records of all children with esophageal...

Noncardiac chest pain is defined as recurrent chest pain that is indistinguishable from ischemic heart pain after a reasonable workup has excluded a cardiac cause. Noncardiac chest pain is a prevalent disorder resulting in high healthcare utilization and significant work absenteeism. However, despite its chronic nature, noncardiac chest pain has no impact on patients' mortality. The main underl...

Aim We report a case of atypical esophageal stricture in a young diabetic woman. Background Diabetes mellitus and gastroesophageal reflux disease (GERD) are two common disorders in modern society. Case report A young diabetic woman developed a 6-cm-long esophageal stricture. This stricture was refractory to multiple esophageal dilation procedures. She underwent subtotal esophagectomy and ha...