PURPOSE Kawasaki disease (KD) is an acute systemic vasculitis. Both the etiology of KD and the erythema of Bacille Calmette-Guérin (BCG) injection sites observed in the disease are poorly understood. We investigated the association between KD and single nucleotide polymorphisms (SNPs) in two candidate genes: inositol 1,4,5-triphosphate 3-kinase (ITPKC), a well-studied KD-associated gene, and so...

BACKGROUND It was proposed that Stevens-Johnson syndrome and toxic epidermal necrolysis differed from erythema multiforme majus by the pattern and localization of skin lesions. OBJECTIVE To evaluate the validity of this clinical separation. DESIGN Case-control study. SETTINGS Active survey from 1989 to 1995 of 1800 hospital departments in Europe. PATIENTS A total of 552 patients and 172...

BACKGROUND Cutaneous injury following impact of a high velocity ball to the skin may result in either erythema or purpura or both. The lesion typically appears as an annular ring of erythema with or without accompanying ecchymosis when the skin is contacted by a paintball, a ping pong ball, a racquetball or a squash ball. PURPOSE To describe a girl with targetoid erythema following impact of ...

ERYTHEMA exudativum multiforme is a specific skin disease of unknown aetiology which may be associated with various syndromes in which the mucous membranes-conjunctiva, lips, bronchi and ano-genital region-are affected, and consequently fall in the domain of the dermatologist, physician, ophthalmologist and uro-genital surgeon. As its name implies, erythema multiforme is characterised by the va...