s | 41 Conclusion: Clinically relevant improvements in psychopathology were observed in patients with acute schizophrenia treated with brexpiprazole or aripiprazole. Brexpiprazole was well tolerated with a lower incidence of EPS-related adverse events than aripiprazole. PM385 Long-term safety of brexpiprazole (OPC-34712) in schizophrenia: results from two 52-week open-label studies Christoph U....

s | 41 Conclusion: Clinically relevant improvements in psychopathology were observed in patients with acute schizophrenia treated with brexpiprazole or aripiprazole. Brexpiprazole was well tolerated with a lower incidence of EPS-related adverse events than aripiprazole. PM385 Long-term safety of brexpiprazole (OPC-34712) in schizophrenia: results from two 52-week open-label studies Christoph U....

We aimed to determine the cytotoxic and immunomodulatory effects of hydroalcoholic extracts of the roots and aerial parts of Ebenus boissieri (EB) on breast cancer MDA-MB231 cells and the non-cancerous human embryonic kidney cell line, 293T. Cell viability was determined by MTT assay, trypan blue exclusion, and Live/Dead Viability/Cytotoxicity assay. Apoptosis was evaluated by measuring the act...

Numerous studies have implicated bacteria in cardiovascular disease, but there is a paucity of information on the mechanism involved. In this study we show how the common oral bacterium Streptococcus sanguis can directly interact with platelets, resulting in activation and aggregate formation. Platelet aggregation was dependent on glycoprotein IIb/IIIa (GPIIb/ IIIa) and thromboxane. Platelets c...

Patients —Texas, Arkansas, and Florida, 2008–2013 Anne Purfield, PhD; Snigdha Vallabhaneni, MD, MPH; Kaitlin Benedict, MPH; Shawn Lockhart, PhD; Cau Pham, PhD; Ulzii Luvsansharav, MD, PhD; Wendy Chung, MD, MSPH; Emily Hall, MPH; Jordan Peart; Neil Pascoe RN, BSN; Gary Heseltine, MD, MPH; Charlotte Wheeler, RN; Karen Brust, MD; Sharon Holmes, MPH; Prinu Gabriel, MS; Justin Groves, MPH; Craig Gil...

Cedar waxwings (Bombycilla cedrorum) feed predominantly on fruits that are rich in simple sugars and low in nitrogen, supplementing this diet with arthropod prey during the summer months as well as flowers and tree sap in springtime. In contrast, thrushes feed extensively on fatty, protein-rich invertebrate prey, supplemented with sugary and lipid-rich fruits. Simple sugars and fats are digeste...

Mites of the subfamily Harpirhynchinae (Acariformes: Cheyletoidea: Harpirhynchidae) associated with neognathous birds (Aves: Neognathae) in the New World are revised. In all, 68 species in 8 genera are recorded. Among them, 27 new species and 1 new genus are described as new for science: Harpyrhynchoides gallowayi Bochkov, OConnor and Klompen sp. nov. from Columba livia (Columbiformes: Columbid...

drugs. In 2011, that CMS “Robin Hood” move resulted in an additional $200 million being tossed into the separately payable-drug reimbursement pool. As a result, the average reimbursement went from a rate of ASP minus 1% (which is what the CMS formula would have dictated) to the ASP plus 5%. That is 1% higher than the 2010 amount. Although hospitals are appreciative of the increase, they point o...

In the family of Euphorbiaceae, the genera Euphorbia and Sapium are known to contain essentially latex-bearing species. In the present study, the latex of Euphorbia selloi (Klotzsch & Garcke) Boiss., Euphorbia papillosa A.St.-Hil., and Sapium glandulosum (L.) Morong, plants native from Brazil, were examined concerning proteolytic activity. All studied species have proteins with significant prot...

The ethnopharmacology of Madeira and Porto Santo Islands is extremely interesting because of the cultural and biogeographic features of this region, which make it a centre of medicinal plant diversity (richness of endemic flora, geographical isolation in the Atlantic sea, crosscultural influences, and past abundance of local healers). The medicinal flora of Madeira is composed of 259 species. S...