Two experiments were performed to investigate subjects' ability to detect and discriminate 50-ms up-glides in frequency in several different conditions. In the first experiment, the subjects indicated which of two signals increased more in pitch. The comparison, or standard signal, was a sinusoid which increased in frequency by either 0, 250, or 500 Hz. Center frequencies were 0.5, 1, 2, 4, and...

We have examined the tissue-specific mRNA expression of ERa and ERb in various bovine tissues using real-time RT-PCR. The goal of this study was to evaluate the deviating tissue sensitivities and the influence of the estrogenic active preparation RALGRO on the tissue-specific expression and regulation of both ER subtypes. RALGRO contains Zeranol (a-Zearalanol), a derivative of the mycotoxin Zea...

BACKGROUND AND PURPOSE Pseudomeningocele is a well-known MR imaging finding in Erb palsy. Our aim was to evaluate the prevalence and imaging features of PST, a lesser known but, in our experience, more common finding in Erb palsy. MATERIALS AND METHODS This retrospective study consisted of 37 subjects with Erb palsy from birth trauma. MR imaging examinations of the brachial plexus were evalua...

This paper reviews the current state of knowledge, advances and challenges in short-wave earth radiation budget (ERB) studies and the cloud absorption anomaly (CAA) debate. The ERB issues deal exclusively with the solar energy disposition between the atmosphere, clouds and the surface. The ERB and its disposition have been derived from surface observations, satellite remote sensing and general ...

The aim of the present study was to investigate the possible contribution of estrogen to pregnancy-associated modulation of nitric oxide production in the human myometrium during pregnancy. Both endothelial nitric oxide synthase (eNOS) and inducible NOS (iNOS) proteins were clearly expressed in the non-pregnant myometrium and were elevated in the ®rst trimester of pregnancy. Oral contraceptive ...

Prostate cancer is the most commonly diagnosed malignancy in men in developed countries. ErbB2, a tyrosine kinase receptor overexpressed in many human cancer types, contributes to prostate cancer progression by activating the androgen receptor in a steroid poor environment, thus promoting androgen-independent cell growth. The consequent development of hormone refractory tumors is a major obstac...

In order to elucidate the relationship between tumor growth and various kinds of gene expression and the occurrence of apoptosis in the front portion of neoplastic invasion, 57 advanced colorectal cancers were studied by immunohistochemical staining of p53, c-erb B-2, the TUNEL method and electron microscopy. Light microscopically, the columnar epithelial cells of adenocarcinoma frequently show...

OBJECTIVES Oral contraceptives (OCP) are highly effective, safe and widely used. Higher exposure to endogenous and exogenous estrogens is generally thought to increase the risk of breast cancer. Therefore, this study was conducted to determine if oral contraceptive use affected the expression of CA 15-3, CEA and C-erb B-2 in the saliva of healthy women. STUDY DESIGN The participants consisted...

The expression of estrogen receptors, ESR1 (ERa) and ESR2 (ERb), and androgen receptors (AR) in the thyroid gland has been reported in few vertebrate species other than a few mammals. This study reports the presence of sex steroid hormone receptors and thyroid receptors (ERa, ERb, AR, TRa, and TRb) in the thyroid gland of the American alligator at several life stages. It provides a semiquantifi...

Combined resistive breathing (CRB) is the hallmark of obstructive airway disease pathophysiology. We have previously shown that severe inspiratory resistive breathing (IRB) induces acute lung injury in healthy rats. The role of expiratory resistance is unknown. The possibility of a load-dependent type of resistive breathing-induced lung injury also remains elusive. Our aim was to investigate th...