childrenwith helicobacter infection need treatment. the aim of treatment is elimination of h.pylori. most patients with this infection are asymptomatic and without peptic disease. treatment and management of these patients are controversy. conventional treatment: the best treatment for h. pylori eradication regimens should have cure rates of at least 80%, be without major side effects, and indu...

Th e most popular regimen for eradication of Helicobacter pylori (H. pylori) infection is triple therapy, composed of a potent proton pump inhibitor (PPI), amoxicillin (AMOX), and clarithromycin (CLA). Emerging resistance to CLA changed this strategy, and according to Maastricht IV recommendation, this regimen can be used only in countries with low (<20%) CLA resistance [1]. A regimen for the t...

Helicobacter pylori infection is one of the most common human infections which have been associated with many upper gasterointestinal complications. Different treatment regimens for Helicobacter pylori eradication have been used. One of these regimes is the quadruple therapy regimen which metronidazole is one of the medications. In recent years several reports on H. pylori res...

Helicobacter pylori is a human pathogen and can lead to chronic gastritis, peptic ulcer disease, gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. H. pylori infection is associated with gastric cancer and has been categorized as a group I carcinogen in gastric cancer. In 2016, Maastricht V/Florence Consensus report emphasized H. pylori infection as an infectious disease and...

End-stage renal disease (ESRD) patients exhibit an increased incidence of peptic ulcer disease. Helicobacter pylori plays a central role in the development of peptic ulcers. The effect of early H pylori eradication on the recurrence of complicated peptic ulcer disease in ESRD patients remains unclear. The aim of the present study was to explore whether early H pylori eradication therapy in ESRD...

OBJECTIVE To do a systematic review and meta-analysis of studies comparing sequential therapy for eradication of Helicobacter pylori with pre-existing and new therapies, thus providing a glimpse of eradication success worldwide. DESIGN Systematic review and meta-analysis. DATA SOURCES Medline, Embase, and Cochrane Central Register of Controlled Trials up to May 2013; abstract books of major...

BACKGROUND The eradication of Helicobacter pylori (H. pylori) can be challenging in certain circumstances. There is no current first-line therapy that is curative in all patients. OBJECTIVE This article summaries the role of emerging novel therapies in the treatment of 
H. pylori. Known as sequential therapy and salvage therapy, these new therapeutic strategies are thought to produce eradicat...