Background The rationale for injection of epidural medications through the needle is to promote sooner onset of pain relief relative to dosing through the epidural catheter given that needle injection can be performed immediately after successful location of the epidural space. Some evidence indicates that dosing medications through the epidural needle results in faster onset and improved quali...

BACKGROUND Epidural analgesia is an effective and popular way to relieve labour pain but it may interfere with normal mechanism of labour. The objective of this study was to evaluate the outcome of labour in women with effective epidural analgesia in terms of duration of labour, mode of delivery and neonatal outcome. METHODS This was a quasi-experimental study conducted in the Department of O...

BACKGROUND Thoracic epidural analgesia is a well established technique for postoperative pain relief after major abdominal and thoracic surgery. Safety remains a major concern because of serious adverse events including epidural haematoma, abscess and permanent neurological deficit. OBJECTIVE The aim of this study was to evaluate the incidence and the long-term outcome of serious adverse even...

BACKGROUND AND METHODS To evaluate the efficacy of postthoracotomy analgesia with intermittent epidural fentanyl. 50 patients were allocated randomly into 2 groups. The first group received intermittent epidural fentanyl and the second group received intermittent intravenous analgesia using pethidine. The variables studied were: pain score; total amount of additional intravenous opioid analgesi...

BACKGROUND This study evaluated the efficacy of an epidural single dose of neostigmine combined with sufentanil to provide selective and balanced analgesia at the beginning of labor. METHODS After informed consent, 125 healthy parturients were randomly allocated to receive, after a test dose, a single injection of either epidural sufentanil 20 micrograms (minimal analgesic dose) or 10 microgr...

BACKGROUND AND OBJECTIVES Clinical effects and the potential synergism between clonidine, an alpha2-adrenergic agonist, and ropivacaine have not been studied in patients undergoing epidural anesthesia. This research aimed at clinically evaluating clonidine associated to ropivacaine for epidural anesthesia. METHODS Participated in this double-blind study 60 patients of both genders who were di...

Purpose: In this study we sought to determine if and when a difference exists with regards to differential sensory blockade between spinal and epidural anaesthesia using lidocaine. Methods : Ten healthy volunteers were randomly assigned to receive both spinal and epidural anaesthesia. Nonepinephrine containing solutions of lidocaine, 100 mg lidocaine 5% with 7.5% dextrose (spinal) and 600 mg li...

BACKGROUND AND PURPOSE Treatment of postoperative pain in children with cerebral palsy (CP) is a major challenge. We investigated the effect of epidural analgesia, high-volume local infiltration analgesia (LIA), and an approximated placebo control on early postoperative pain in children with CP who were undergoing unilateral hip reconstruction. PATIENTS AND METHODS Between 2009 and 2014, we i...

TO the Editor-I read with interest the study by Boylan et al.' comparing epidural bupivacaine-morphine analgesia with patient-controlled analgesia after abdominal aortic surgery. However, I have a major concern. After a loading dose of 1 0 ml of 2% lidocaine followed by 15 ml of 0.25%) bupivacaine via a lumbar epidural catheter, sensory block in the epidural group was probably at an adequate th...