The osmotic challenges facing maturing spermatozoa and their responses to them are discussed in relation to the concept of sperm maturation, defined as the increased ability of more distally recovered epididymal spermatozoa to fertilize eggs when inseminated into the female tract. One explanation could be that the more distal cells are better able to regulate their volume, and reach the oviduct...

Although various contraceptive methods and medications have been devised so far,there is no ideal male contraceptive agent,free from side effects and without adverse effects on secondary sexual  characterestics and sexual behaviour.in this study the antifertility effects of furazolidone on the process of spermatogenesis in adelt male rats have been evaluated.the results indicate that this drug ...

Objective: Microsurgical reconstruction is recommended for obstructions in the vas deferens and epididymis. However, intracytoplasmic sperm injection (ICSI) is the preferred therapy and microsurgical vasoepididymostomy (MVE) may be neglected for patients with epididymal obstruction. Fertility outcomes from large sample are absent. In this study we aimed to investigate the pregnancy and live bir...

This review briefly summarises the cellular and physiological aspects of sperm motility (SM) and viability from the point of view of male fertility/infertility. We discuss the SM patterns and maturation processes during the epididymal transit, including the effects of seminal plasma proteins, and while moving through the female reproductive tract. In connection with SM and viability, the oxidat...

Comments on "Is Sperm Motility Maturation Affected by Static Magnetic Fields?" In the paper titled "Is Sperm Motility Maturation Affected by Static Magnetic Fields?" (1), the authors conclude that "sperm production is unaffected because no changes were observed in testicular or epididymal weights after exposure to static magnetic fields." This conclusion, however, is not supported by the data p...

In this study, we conducted a simultaneous analysis of sperm count and viability in rats by flow cytometry (FCM). Epididymal fluids were taken from the caudal epididymis of 12 to 13 week-old Sprague-Dawley rats. The fluids were weighed and mixed with Dulbecco's phosphate buffered saline (D-PBS). Propidium iodide, which can stain only dead sperm, was used to distinguish viable and dead sperm. Th...

Background: About 90% of the world’s contraceptive users are women. This gender-based usage has occurred due to the emphasis of family planning programs and contraception research. Condom, vasectomy and withdrawal are the only male contraception devices available with less assurance for men. For new male contraceptive to have an impact, they must be acceptable to both men and women, as well as ...

BACKGROUND A bulk of contraceptives on the market is women-oriented today. The aim of this study was to investigate the effect of a medicinal herb, Acacia nilotica on various parameters of male fertility using a rat model. METHODS Male Wistar rats (n = 40) were randomly divided in to two groups. One group received Acacia nilotica, while the other acted as controls. Ten animals from each group...