Despite recent attempts to define and classify patients with marked eosinophilia and features consistent with myeloproliferative disease, areas of controversy remain. These are particularly apparent in situations in which multiple lineages are involved in a clonal process and clinical manifestations are overlapping. Although the introduction of new molecular diagnostics and targeted therapies h...

Eosinophilic gastroenteritis is an uncommon condition characterized by focal or diffuse infiltration of eosinophils in the gastrointestinal tract in the absence of secondary causes. The pathogenesis of this condition is not well understood and its clinical presentation depends on the segment and layer of the gastrointestinal tract affected. The definition of eosinophilic gastroenteritis may be ...

Background Food allergy is an adverse health effect arising from a specific immune response that occurs reproducibly on exposure to a given food. Food allergies are classified into three types: Ig(immunoglobulin)E mediated, mixed IgE and cell mediated and cell-mediated non IgE mediated. Gastrointestinal (GIT) food allergy has classically encompassed a number of different clinical entities: food...

1-year history of watery diarrhea and gradual weight loss. One week before admission, the frequency of watery diarrhea increased up to six times per day, accompanied by hematochezia and lower abdominal pain. The patient denied any prior history of systemic disease or medications. Laboratory evaluation revealed normal leukocyte count (8.7 × 109/L [normal 4.0–10.8 × 109/L]) with marked peripheral...

herself to the emergency room with dysphagia 18 hours after ingesting a tablet of paracetamol. She had suffered from multiple episodes of dysphagia before. As shown in l" Fig. 1, an upper gastrointestinal series radiograph taken after admission revealed obstruction of the proximal third of the esophagus. Emergency esophagoscopy revealed a dilated esophagus and the tablet at the end of the oral ...

Idiopathic eosinophilic gastroenteritis is a rare inflammatory disease of unknown origin, characterized by diffuse eosinophilic infiltration of the gastrointestinal tract, accompanied by varying abdominal symptoms related to the location, severity and depth of invasion. Any part of the gastrointestinal tract including the esophagus may be involved, although the stomach and small bowel are the m...