Human enteric pathogenic viruses can enter the environment through discharge of waste materials from infected persons, and be transmitted back to susceptible persons to continue the cycle of disease. Contamination of food with viruses may also promote disease outbreaks. A number of studies have investigated the survival characteristics of several enteric viruses in various environments and food...

    In this double blind crossover study we assessed the bioequivalence of 200 mg enteric coated sodium valproate tablets manufactured by Roozdarou with 200 mg enteric coated sodium valproate (Orlept) manufactured by Desitin, Germany. Twelve healthy male volunteers were administered a single dose of 600 mg sodium valproate manufactured by Roozdarou, followed by a similar dose of Orlept, 2 weeks...

BACKGROUND Common enteric pathogens that cause gastrointestinal illness are transmitted to humans through food, water or direct contact. This poses a significant concern to public health as enteric pathogens can cause disease in a large number of people, and cost a substantial amount to treat and prevent. In order to gain a better understanding of the occurrence of enteric disease in Ontario, t...

The inflammatory bowel diseases are complex, idiopathic disorders whose pathogenesis is beginning to be understood largely due to the generation and investigation of many experimental models over the past decade. In most of these models, the enteric microbial bacteria are obligatory for disease expression, and in most, CD4 T-cells are the effector cells mediating chronic intestinal inflammation...

Abdominal and pelvic abscesses occur in approximately 10-30% of Crohn's disease patients during the course of the disease; most of these abscesses have an enteric communication. For this condition, percutaneous abscess drainage (PAD) rather than emergency surgery has recently been recognized as a valuable procedure for initial treatment. However, in cases wherein the abscess is accompanied by a...

Simultaneous detection of enteric viruses that cause similar symptoms (e.g. hand, foot and mouth disease) is essential to the prevention of outbreaks and control of infections. In this study, a novel PCR-Mass assay combining multiplex polymerase chain reaction (PCR) with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) was developed and used for simult...