Previous studies have shown that P19 cells expressing a dominant negative β-catenin mutant (β-cat/EnR) cannot undergo myogenic differentiation in the presence or absence of muscle-inducing levels of retinoic acid (RA). While RA could upregulate premyogenic mesoderm expression, including Pax3/7 and Meox1, only Pax3/7 and Gli2 could be upregulated by RA in the presence of β-cat/EnR. However, the ...

The substantial use of triclosan (TCS) has been aimed to kill pathogenic bacteria, but TCS resistance seems to be prevalent in microbial species and limited knowledge exists about TCS resistance determinants in a majority of pathogenic bacteria. We aimed to evaluate the distribution of TCS resistance determinants in major pathogenic bacteria (N = 231) and to assess the enrichment of potentially...

BACKGROUND Enoyl-ACP reductase (ENR) catalyses the last reduction reaction in the fatty acid elongation cycle in bacteria and is a good antimicrobial target candidate. FabV is the most recently discovered class of ENR, but we lack information about the atomic structure and the key residues involved in reductase activity except for the known conserved tyrosine and lysine residues in the Y-X(8)-K...

This paper presents a broadband-noise circuit model for a “cold”-FET (Vds 0 V) with a reverse-biased gate. The noise model includes two intrinsic uncorrelated noise-current sources whose spectral densities are determined from measurement of the device’s S parameters and noise powers. The model is used to characterize the device’s excess Figure 3 Radiation patterns in the (a) x–z and (b) y–z pla...

Currently, a range of sectors are implementing three-dimensional (3D) printing, which is part additive manufacturing (AM) technology via the fused deposition modelling (FDM) approach. As now, various filament materials available in market and have their limitations. Thermoplastic elastomer (TPE) blend as material 3D printing should be implemented to overcome weakness filaments. TPE stands out d...