OBJECTIVE To characterize the epidemiology of wasting and identify the main predictors of wasting, severe wasting and poor weight-for-height in children. DESIGN We analysed a nationally representative sample of 2028 children (Multiple Indicator Survey, 2010). SETTING Royal Kingdom of Bhutan. SUBJECTS Children aged 0-23 months. RESULTS Wasting prevalence was significantly higher among in...

Malnutrition (wasting or cachexia) is frequently observed in uraemic patients, both in the predialysis phase and during renal replacement therapy [1,2]. According to the DOPPS, every 4th to 5th dialysis patient suffers from moderate or severe malnutrition [3]. It was also found that dietary energy and protein intakes are inadequate in the majority of haemodialysis patients [4]. For many years, ...

Protein energy wasting (PEW) is an independent factor associated with morbi-mortality in chronic kidney disease. Wasting is particularly common in chronic diseases of organs such as kidney disease with a major impact at the stage of dialysis. It covers 20 to 70% of patients diagnosed with chronic kidney disease according to the degree of evolution of the disease and the diagnostic method used p...

Sarcopenia is a condition of multifaceted etiology arising in many elderly people. In patients with chronic kidney, the loss of muscle mass is much more intensive and the first signs of sarcopenia are observed in younger patients than it is expected. It is associated with the whole-body protein-energy deficiency called protein-energy wasting (PEW). It seems to be one of the major factors limiti...

BACKGROUND Muscle wasting is a common complication in patients with infantile nephropathic cystinosis, but its mechanism and association with energy metabolism is not known. We define the metabolic phenotype in Ctns(-/-) mice, an established murine model of infantile nephropathic cystinosis, with focus on muscle wasting and energy homeostasis. METHODS Male Ctns(-/-) mice and wild-type (WT) co...

BACKGROUND The long-term consequences of wasting among HIV-infected persons are not known. DESIGN HIV-infected men surviving ≥2 years based on Kaplan-Meier analysis after a clinical diagnosis or weight trajectory consistent with wasting and with available physical function assessment data [grip strength, gait speed, and quality of life (QoL)] were matched to HIV-infected and uninfected men wi...