نتایج جستجو برای: energy release rate
تعداد نتایج: 1750353 فیلتر نتایج به سال:
Introduction: Mathematical modeling of drug release is one of the ways to improve the rate of drug diffusion and infiltration in swollen hydrogel based systems. Using this method can provide a better understanding of the mechanisms of drug control and its release. Hydrogels are a swollen biomaterial that needs to be controlled for use in drug release. Purpose and methodology: In this study, fiv...
The aim of this study was to develop a derivative of chitosan as pharmaceutical excipient used in sustained-release matrix tablets of poorly soluble drugs. A water-soluble quaternary ammonium carboxymethylchitosan was synthesized by a two-step reaction with carboxymethylchitosan (CMCTS), decylalkyl dimethyl ammonium and epichlorohydrin. The elemental analysis showed that the target product with...
Objective(s): In this work, electrospun nanofibers were explored as drug delivery vehicles using tetracycline as a model drug. Nanocomposite fibers including chitosan (CS)/poly (ethylene oxide) (PEO) and antibiotic were successfully prepared using electrospinning. CS blended with PEO considering a weight ratio of (90/10), and then, nanofibrous samples were successfully e...
This study examines the controlled release behavior of both water-soluble (acetaminophen, caffeine, theophylline and salicylic acid) and water insoluble (indomethacin) drugs derived from Caesalpinia pulcherrima seed Gum isolated from Caesalpinia pulcherrima kernel powder. It further investigates the effect of incorporating diluents such as microcrystalline cellulose and lactose on caffeine rele...
The effect of stitching on mode I and mode II strain energy release rates for debond configurations is studied using an analysis based on plate finite elements and the virtual crack closure technique. The stitches were modeled as discrete nonlinear fastener elements with a compliance determined by experiment. The axial and shear behavior of the stitches was considered with both the compliances ...
Phosphorus (P) after nitrogen limits agricultural production in most region of the world. Information about P release rate is limited in Hamadan soils. The objective of this research was to study P release in 10 soils from Hamadan province by successive extraction with 0.5 M NaHCO over a period of 1752 h and the correlation of P release characteristics with soil properties and corn plant (Zea...
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