Endotoxemia is thought to induce severe changes in coagulation status. In this study, blood samples from six beagle dogs receiving 1 mg/kg E. coli lipopolysaccharide (LPS) intravenously were analyzed describe the concurrent platelet count, function assessed with impedance thromboaggregometry, thromboelastometry and d-dimers during artificially induced endotoxemia its therapy fluids vasopressors...

Background: While the hemodynamic effects of terlipressin on reduction hepatic venous pressure gradient are well known, there is a limited information available non- this drug in patients with acute variceal bleeding (AVB). The present study evaluated systemic inflammation and endotoxemia cirrhosis during an episode AVB. Methods: In prospective pilot study, peripheral blood sample was withdrawn...

In vivo endotoxin infusion produces neutrophil-mediated acute lung injury and increases superoxide anion release from phorbol myristate acetate (PMA) -stimulated blood neutrophils collected 18-24 hours after the infusion. Because the turnover time of circulating blood neutrophils is only 6-8 hours, it was hypothesized that the prolonged increase in superoxide anion release from peripheral blood...