This article aims to test the hypothesis that the risk of epithelial ovarian cancer (EOC) in women with endometriosis might be changed by enrolling different population. A nationwide 14-year historic cohort study using the National Health Insurance Research Database (NHIRD) of Taiwan and the Registry for Catastrophic Illness Patients was conducted. A total of 239,385 women aged between 20 and 5...

INTRODUCTION The prevalence of endometriosis and the need for treatment in the USA has led to the need to explore the contemporary cost burden associated with the disease. This retrospective cohort study compared direct and indirect healthcare costs in patients with endometriosis to a control group without endometriosis. METHODS Women aged 18-49 years with endometriosis (date of initial diagn...

OBJECTIVE To assess the impact of endometriosis on health-related quality of life (HRQoL) and work productivity. DESIGN Multicenter cross-sectional study with prospective recruitment. SETTING Sixteen clinical centers in ten countries. PATIENT(S) A total of 1,418 premenopausal women, aged 18-45 years, without a previous surgical diagnosis of endometriosis, having laparoscopy to investigate...

STUDY QUESTION How patient-centered are two included specialized endometriosis clinics relative to each other and how can they improve the patient-centeredness of their care? SUMMARY ANSWER The validated ENDOCARE questionnaire (ECQ) reliably concluded that the adjusted overall patient-centeredness did not differ between the clinics, that each clinic was significantly more patient-centered for...

Purpose: Mechanisms of immune dysregulation associated with advanced tumors are relatively well understood. Much less is known about the role of immune effectors against cancer precursor lesions. Endometrioid and clear-cell ovarian tumors partly derive from endometriosis, a commonly diagnosed chronic inflammatory disease. We performed here a comprehensive immune gene expression analysis of pelv...

Introduction: Endometriosis is a chronic and benign disease that affects women of reproductive age, characterized by the growth endometrial cells outside uterine cavity, resulting in an inflammatory reaction may be associated with occurrence several comorbidities. Objective: To trace relationship between social development indices difficulty diagnosing endometriosis. Methodology: This literatur...

STUDY QUESTION Is there a difference in functional outcome between conservative versus radical rectal surgery in patients with large deep endometriosis infiltrating the rectum 2 years postoperatively? SUMMARY ANSWER No evidence was found that functional outcomes differed when conservative surgery was compared to radical rectal surgery for deeply invasive endometriosis involving the bowel. W...

OBJECTIVE To investigate the association between preceding endometriosis and gestational hypertension-preeclampsia (GH-PE). METHODS In this nationwide population-based longitudinal study, data from 1998-2012 Taiwan National Health Insurance Research Database were used. We used ICD9-CM codes 617.X and 642.X respectively for the diagnoses of endometriosis and GH-PE, which were further confirmed...

Background Endometriosis, defined by overgrowth of endometrial implants outside the uterine cavity, is commonly found on the ovaries. The role of exercise in this disease is not well understood. Regular exercise appears to have protective effects against endometriosis that involve inflammatory processes since it induces elevate systemic levels of inflammatory cytokines production with antioxida...

Background Endometriosis is defined as overgrowth of endometrial tissue outside the uterine cavity. Diet may play a role in the aetiology of endometriosis through effects on oxidative stress, prostaglandin metabolism, and steroid hormone levels. The objective of this paper is to assess the role of diet on risk of endometriosis among infertile Iranian women. MaterialsAndMethods In this case cont...