Worldwide, anthropogenic contaminants emerge and enter into aquatic systems; their ubiquity in aquatic systems poses serious threats to both human health and ecological systems. As the demand for water continues to grow with population, treatment of wastewater and remediation of polluted aquatic systems are of critical concern. Ozonation and advanced oxidation processes (AOPs) are promising met...

Various adverse effects of endocrine disruptors on the reproductive organs of male animals have been reported. We found that UDP-glucuronosyltransferase (UGT) activities towards bisphenol A, testosterone and oestradiol were significantly decreased in liver microsomes prepared from adult male Wistar rats administered with the endocrine disruptor bisphenol A (1 mg/2 days for 2 or 4 weeks). Howeve...

Systems pharmacology is an emergent area that studies drug action across multiple scales of complexity, from molecular and cellular to tissue and organism levels. There is a critical need to develop network-based approaches to integrate the growing body of chemical biology knowledge with network biology. Here, we report ChemProt, a disease chemical biology database, which is based on a compilat...