A coamplification PCR test for the direct detection of Neisseria gonorrhoeae and Chlamydia trachomatis in urethral and endocervical swabs and urine samples from men and women was compared to standard culture techniques. Processed specimens were amplified in single reaction tubes containing primers for both organisms, and PCR products were detected by a colorimetric microwell plate hybridization...

Aztreonam, 1 g intramuscularly, was compared with spectinomycin, 2 g intramuscularly, for uncomplicated gonorrhea. There were no failures with either drug. For aztreonam, there were 26 urethral, 3 rectal, and 3 endocervical sites that were infected. Aztreonam in a single dose of 1 g intramuscularly is satisfactory therapy for uncomplicated urethral gonorrhea in men and may be effective for rect...

This retrospective study refers to the evolution rate of cervical lesions diagnosed from cervical biopsies, respectively the endocervical scrape collected from 2001 to 2008 and found its place as an introduction to a further complex study. In this period of 8 years, in our laboratory were processed a total of 1387 biopsies and endocervical scrape. All histopathological diagnoses can be classifi...

THE PRESENCE of tissue-specific antigen in various mucins has been demonstrated in a number of studies (Bara et al., 1977; Hillermanns, 1962; Nairn et al., 1962). Antibodies to mucins from alimentary tract can be readily produced and shown by immunofluorescence to localize to endosecretory parts of the epithelial cells. More recently, Gold & Miller (1978) showed that, while common gastrointesti...

Chlamydia trachomatis causes a predominantly asymptomatic, but generally inflammatory, genital infection that is associated with an increased risk for HIV acquisition. Endocervical epithelial cells provide the major niche for this obligate intracellular bacterium in women, and the endocervix is also a tissue in which HIV transmission can occur. The mechanism by which CT infection enhances HIV s...

The accuracy of conization for the prediction of radical hysterectomy (RH) pathological variables in patients with stage Ia2 to Ib1 (≤2 cm) cervical cancer was retrospectively evaluated in the present study. Endocervical or deep resection margin (RM) involvement in the conization specimens was found to be independently associated with residual disease in the hysterectomy specimens (P < 0.001, =...

June 29, 2011 The patient was a 30 year old female patient, para 0, who was diagnosed to have a cervical adenocarcinoma on a screening PAP smear. A subsequent endocervical curettage revealed a moderately differentiated adenocarcinoma with focal invasion. She underwent a cone biopsy and a repeated endocervical curettage which revealed an adenocarcinoma in situ with two foci of microinvasion cons...

Papanicolaou smears have false-negative rates of 6 percent to 56 percent that are due, in large part, to inadequate sampling of endocervical cells. A randomized, prospective trial was conducted comparing the adequacy of Papanicolaou smears obtained with the cytobrush and Ayre spatula with smears obtained with the extended-tip spatula, as measured by the presence of endocervical cells. One hundr...