Continuous ambulatory peritoneal dialysis (CAPD) is now a standard therapeutic modality of end-stage renal disease (ESRD) (1). About 80% of ESRD patients in Hong Kong are treated by CAPD. Peritoneal dialysis (PD) related infections, notably peritonitis, are major complications leading to patient morbidity, mortality and technique failure. In this issue, we have two papers addressing these probl...

Cardiovascular disease is a major concern for patients with end-stage renal disease (ESRD), especially those on hemodialysis. ESRD patients with coronary artery disease often do not have symptoms or present with atypical symptoms. Coronary lesions in ESRD patients are characterized by increased media thickness, infiltration and activation of macrophages, and marked calcification. Several studie...

background: chronic kidney disease is a progressive and irreversible loss of renal function. anemia is one of the main complications of end-stage renal disease (esrd) which is linked closely with other complications of the disease. the primary therapy for anemia in these patients is erythropoietin (epo). the goal of this study was to find the effect of vitamin d administration in addition to th...

Although malignancy is a fatal complication of end-stage renal disease (ESRD) requiring haemodialysis, successful treatment of haematological malignancies has been rarely reported. We describe the case of a 64-year-old man who presented with non-Hodgkin's lymphoma (NHL; clinical stage, IVB) concomitant with ESRD. Before chemotherapy, haemodialysis was initiated, and one course of dose-adjusted ...

Cardiovascular disease is a major cause of morbidity and mortality in young adults with end-stage renal disease (ESRD), but its basis is still not well understood. We therefore evaluated the determinants of atherosclerosis in children with ESRD. A total of 37 children with ESRD (with 31 who had undergone transplantation) were examined and compared to a control group comprising 22 healthy childr...

Family history of renal disease has been associated with an increased risk of end-stage renal disease (ESRD). It is uncertain whether this risk is mediated by familial aggregation of risk factors for ESRD, such as diabetes and hypertension. The association of ESRD with familial aggregation of renal disease was examined in a large, population-based case-control study conducted in Maryland, Virgi...

Continuous venovenous hemodiafiltration (CVVHDF) using solutions designed to maintain hypernatremia is described in an end-stage renal disease (ESRD) patient with cerebral edema (CE) due to an intracerebral hemorrhage (ICH). Hypernatremia was readily achieved and maintained without complication. CVVHDF should be considered as an alternative treatment option in ESRD patients with cerebral edema ...

Renal transplant is now the accepted mode of treatment of end stage renal disease (ESRD). The major causes of ESRD being diabetes mellitus, hypertension, glomerulonephritis, polycystic kidney disease and other/unknown. The most common glomerular disease in renal allograft biopsies is transplant glomerulopathy, i.e., those lesions related to transplant rejections. Other glomerulonephropathies (G...

background: it has been shown that serum total homocysteine (hc) is a risk factor for vascular disease which characterizes endothelial damage in the general and in the end-stage renal disease (esrd) population as well. whether n-3 polyunsaturated fatty acids decrease homocysteine (hcy) level has been a subject of controversy. methods: renal transplant patients were randomized in 2 groups and re...

OBJECTIVE Advanced oxidation protein products (AOPPs) represent dityrosine-containing cross-linked protein modifications formed mainly via myeloperoxidase reaction, supposed to accelerate the uremia-associated atherogenesis and renal fibrosis. DESIGN, SUBJECTS, AND MAIN OUTCOME MEASURES: In a cross-sectional study, we investigated the accumulation of AOPPs and advanced glycation end product (AG...