BACKGROUND Mycotic pseudoaneurysm from the cavernous segment of the internal carotid artery (ICA) secondary to an invasive aspergillus sinusitis is rare. Surgical intervention with ICA ligation is generally accepted for most mycotic aneurysms or pseudoaneurysms. When presented with massive epistaxis due to a fungal aspergillus ICA invasion, mortality rates are high. METHODS We present the cas...

Recent studies have shown that drugs that are normally unable to cross the blood-brain barrier (BBB) following intravenous injection can be transported across this barrier by binding to poly(butyl cyanoacrylate) nanoparticles and coating with polysorbate 80. However, the mechanism of this transport so far was not known. In the present paper, the possible involvement of apolipoproteins in the tr...

Cyrany J, Kopáčová M, Rejchrt S, Krajina A, Bureš J. Gastric arterial bleeding secondary to chronic occlusion of the splenic artery. Folia Gastroenterol Hepatol 2004; 2 (2): 92 98. Abstract. The authors present exceptional case of life threatening bleeding from fundic arterial collaterals in the patient with atherosclerotic chronic occlusion of the splenic artery. Haemostasis was achieved by en...

Background: To evaluate the hemostatic effects of emergent Eendoscopic Variceal Sclerotherapy (EIS) combined with acrylate glue (N-butyl-2-cyanoacrylate, NBCA) injection (ESCI) on esophageal variceal bleeding, and to investigate glue extrusion after endoscopic injection. Methods: The rate of hemostasis and blood transfusion in patients that received ESCI were compared to 16 patients who receive...

BACKGROUND We sought to determine the efficacy of sutures, human fibrin glue and N-butyl-2-cyanoacrylate for mesh fixation in patients undergoing the plug and mesh procedure for groin hernia. METHODS A total of 156 patients with 167 inguinal hernias (11 bilateral) underwent a plug and mesh procedure and were randomly assigned to received either sutures (n = 59 hernias), human fibrin glue (n =...

As the majority of the polymers used as cardiovascular grafts so far do not match the elasticity of human arteries (100-1000kPa) and the required endothelialization, a multifunctional material approach is needed to allow the adjustment of the mechanical properties while at the same time exhibiting a haemocompatible surface. Recently soft poly(n-butyl acrylate) networks (cPnBA) with adjustable m...

The purpose of this study was to determine the effects of 6-amino-2-[2-(4-tert-butyl-phenoxy)-ethylsulfonyl]-1H-pyrimidine-4-one (DL3), a novel synthetic compound with small-molecule drug properties, on androgen-regulated gene expression and cell growth in human prostate cancer cells. LNCaP, 22Rv1, and LAPC-4 cells were used in the studies. Expression of prostate-specific antigen (PSA) and andr...

Polymer electrolyte films, comprising ammonium trifluoromethanesulfonate salt and butyl-trimethyl ammonium bis(trifluoromethylsulfonyl)imide ionic liquid immobilized in poly (ethyl methacrylate) was studied. Structural, morphological, thermal and electrical properties of the polymer electrolyte films were investigated by differential scanning calorimetry, scanning electron microscopy, and imped...

PURPOSE The purpose of this study was to report on splenic artery aneurysms (SAAs) treated by transcatheter embolization in our single-center institution and to evaluate the clinical outcomes of patients with SAA by aneurysm location. MATERIALS AND METHODS The original medical records and imaging results of 52 patients with SAA treated in our center between January 1, 1995 and December 31, 20...

BACKGROUND AND PURPOSE Intracerebral hemorrhages after embolization of arteriovenous malformations (AVMs) are the most dreaded complications of this well-established therapy. Apart from the known risk factors, our center noticed a high incidence of complications during postinterventional monitoring in medical intensive care units (ICUs) and stroke units. MATERIALS AND METHODS We report 125 co...