Organic semiconductor nanoparticles provide a potentially scalable approach for photovoltaics that can be processed from aqueous media. Particles of poly(3-hexylthiophene) (P3HT):phenyl-C61-butyric acid methyl ester (PCBM) were prepared using two techniques; those produced by a mini-emulsion method contained greater amounts of crystalline P3HT domains with charge generation resembling phase-sep...

A solution-processed patterning of functional organic materials in emulsion is reported. The concept is to absorb microdrops onto predefined locations by hydrophilicity difference. Owing to a universal solvent used, the method can be applied to pattern variety materials on substrates of interest over large size. The figure shows Rhodamine 6G patterned film.

Microspheres ketoprofen (KP) were prepared by o/w emulsion solvent evaporation technique using EudragitRS100 as a polymeric material. The effect of process variables such as drug: polymer ratio, stirring rate, emulsifier concentration, internal organic solvent and dispersing medium volumes were examined. The prepared formulations were characterized for particle size distribution, percent yield,...

The development of nonviral vectors for the efficient and safe delivery to cells has long been awaited to facilitate gene therapy. Recently, many nonviral vectors modified with cationic lipids, cationic polymers, etc. have been reported. However, those nonviral vectors with cationic materials require improved stability, longer duration of gene expression, and reduced cytotoxicity. We successful...

The cause of initial burst release of hydrophilic macromolecular drugs from biodegradable polymeric microspheres was identified. Poly(D,L-lactic-co-glycolic acid) microspheres encapsulating fluorescein isothiocyanate (FITC)-labled dextran was prepared by a double emulsion solvent evaporation method. The extent of initial burst release was examined by varying the formulation process conditions s...

INTRODUCTION The purpose of this investigation was to evaluate microencapsulated controlled release preparation of theophylline using Eudragit RS 100 as the retardant material with high entrapment efficiency. METHODS Microspheres were prepared by the emulsion-solvent evaporation method. A mixed solvent system consisting of methanol and acetone and light liquid paraffin as oily phase were chos...

The purpose of this study was to design novel drug delivery system containing Lornoxicam microsponges. Lornoxicam is a Non-steroidal anti-inflammatory drug used for the treatment of various inflammatory diseases. Microsponges containing Lornoxicam and Eudragit RS 100 were prepared by quasi emulsion solvent diffusion method. The effects of drug to polymer ratios on physical characteristics of th...

The objective of the current investigation is to reduce dosing frequency and improve patient compliance by designing and systematically evaluating sustained release microspheres enriched gel of econazole nitrate. An antifungal agent, Econazole nitrate, is delivered through the microparticulate system using ethyl cellulose as the controlled release polymer. Microspheres were developed by the emu...

Purpose: To prepare and evaluate floating microspheres of curcumin for prolonged gastric residence time and increased drug bioavailability. Methods: Floating microsphere were prepared by emulsion solvent diffusion method, using hydroxylpropyl methylcellulose (HPMC), ethyl cellulose (EC), Eudragit S 100 polymer in varying ratios. Ethanol/dichloromethane blend was used as solvent in a ratio of 1:...

The objective of the current investigation is to reduce dosing frequency and improve patient compliance by designing and systematically evaluating sustained release microballoons of Propranolol hydrochloride. An antihypertensive drug, Propranolol hydrochloride, is delivered through the microparticulate system using ethyl cellulose as the controlled release polymer. Microballoons were developed ...