OBJECTIVES To evaluate the interobserver reliability of echocardiographic findings of right ventricle (RV) dysfunction for prognosticating normotensive patients with pulmonary embolism (PE). METHODS A central panel of cardiologists evaluated echocardiographic studies of 75 patients included in the PROTECT study for the following signs: RV diameter, RV/left ventricular (LV) diameter ratio, hyp...

Bronchopulmonary dysplasia (BPD) is a chronic lung disease associated with under development of lung tissue, mainly occurring in premature and extremely low birth weight infants. BPD has a poor prognosis in morbidity and mortality but BPD with pulmonary hypertension and right ventricular (RV) dys-function has worse prognosis. 1) Early detection for pulmonary hypertension and RV dysfunction is i...

Attenuated tissue culture-adapted and natural street rabies virus (RV) strains differ greatly in their neuroinvasiveness. To identify the elements responsible for the ability of an RV to enter the CNS from a peripheral site and to cause lethal neurological disease, we constructed a full-length cDNA clone of silver-haired bat-associated RV (SHBRV) strain 18 and exchanged the genes encoding RV pr...

BACKGROUND Many patients with congenital heart disease develop right ventricular (RV) failure due to anatomy and prior therapy. RV problems may include right bundle-branch block (RBBB), volume loading, and chamber enlargement. Because the failing RV may have regional dyskinesis, we hypothesized that resynchronization therapy might augment its performance. METHODS AND RESULTS We studied 7 pati...

Abstract In this work, the non-liner voltage distribution in transformer winding is investigated that occurs due switching and lightning. Transformer winding is modeled in the alternative transients program (ATP) version of Electromagnetic transients program (EMTPRV). EMTP software is used to simulate the very fast transient overvoltage. An experimental setup that consist of , Recurrent surge g...

This paper is concerned with lightning surge propagation on wind turbines. As wind power generation undergoes rapid growth, lightning incidents involving wind turbines have come to be regarded as a serious problem. Nevertheless, no known studies exist yet in Portugal regarding lightning protection of wind turbines. In this paper we present an overview of Electro-Magnetic Transients Program (EMT...

Right ventricle (RV) dysfunction occurs with progression of pulmonary arterial hypertension (PAH) due to persistently elevated ventricular afterload. A critical knowledge gap is the molecular mechanisms that govern the transition from RV adaptation to RV maladaptation, which leads to failure. Here, we hypothesize that the recently established mouse model of PAH, via hypoxia and SU5416 treatment...

Recombinant rabies virus (RV)-based vectors have demonstrated their efficacy in generating long-term, antigen-specific immune responses in murine and monkey models. However, replication-competent viral vectors pose significant safety concerns due to vector pathogenicity. RV pathogenicity is largely attributed to its glycoprotein (RV-G), which facilitates the attachment and entry of RV into host...

BACKGROUND Right ventricular (RV) failure is the most important factor of both morbidity and mortality in pulmonary arterial hypertension (PAH). However, the underlying mechanisms resulting in the failed RV in PAH remain unknown. There is growing evidence that angiogenesis and microRNAs are involved in PAH-associated RV failure. We hypothesized that microRNA-126 (miR-126) downregulation decreas...