Background—Periodontal disease results in the loss of the attachment apparatus. In the last three decades, an increasing effort has been placed on seeking procedures and materials to promote the regeneration of this tissue. The aim of this paper is to evaluate the effect of enamel matrix derivative (EMD) during regenerative procedures. In addition, a meta-analysis is presented regarding the cli...

BACKGROUND Periodontal disease results in the loss of the attachment apparatus. In the last three decades, an increasing effort has been placed on seeking procedures and materials to promote the regeneration of this tissue. The aim of this paper is to evaluate the effect of enamel matrix derivative (EMD) during regenerative procedures. In addition, a meta-analysis is presented regarding the cli...

BACKGROUND Myofilament Ca(2+) sensitizers enhance contractility but can adversely alter diastolic function through sensitization to low intracellular Ca(2+) concentration. Concomitant phosphodiesterase III inhibition (PDE3I) may offset diastolic changes but limit the mechanoenergetic benefits. We tested whether selective Ca(2+) sensitization in vivo with the use of EMD-57033 enhances both systo...

In this paper, we propose some recent works on data analysis and synthesis based on Empirical Mode Decomposition (EMD). Firstly, a direct 2D extension of original Huang EMD algorithm with application to texture analysis, and fractional Brownian motion synthesis. Secondly, an analytical version of EMD based on PDE in 1D-space is presented. We proposed an extension in 2D-case of the so-called “si...

BACKGROUND Limited orthodontics are shown to be effective in the correction of infrabony defects. Studies have also demonstrated the efficacy of using enamel matrix derivative (EMD) with demineralized freeze-dried bone allograft (DFDBA) to treat infrabony defects. This study aims to compare the clinical efficacy of limited orthodontics combined with EMD/DFDBA in the treatment of 2- or 3-wall in...

In this paper, to recover the missing geometry details on 3D surfaces, we develop a novel geometry detail recovery algorithm for 3D surfaces based on Empirical Mode Decomposition (EMD). EMD is a powerful tool for processing non-linear and non-stationary signals and has been successfully used in 3D surface analysis and processing. Given a signal defined on 3D surface, EMD could represent the sig...

The Empirical Mode Decomposition (EMD) is a popular algorithm used for the processing of non-linear and non-stationary signals. In this paper we implemented the EMD algorithm and study the use of EMD in broad range of applications for extracting data from the signals. It decomposes the signal into highly varying Intrinsic Mode Functions (IMF) and slowly varying residues. Finally the results are...

This paper presents a novel algorithm of speech enhancement using data adaptive softthresolding technique. The noisy speech signal is decomposed into a finite set of band limited signals called intrinsic mode functions (IMFs) using empirical mode decomposition (EMD). Each IMF is divided into fixed length subframes. On the basis of noise contamination, the subframes are classified into two group...

EMD 53998 (a thiadiazinone) is an inotropic drug that produces a pronounced increase in the Ca2+ sensitivity of the contractile proteins in skinned cardiac fibers. The present study was undertaken to determine whether this effect on Ca2+ sensitivity could explain the increase in tension observed in intact ventricular muscle. The experiments were performed on isolated ferret papillary muscles th...

Induction of drug-metabolizing enzymes (DMEs) is highly species-specific and can lead to drug-drug interaction and toxicities. In this series of studies we tested the species specificity of the antidiabetic drug development candidate and mixed peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist (S)-4-O-tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric acid (EMD 392949, EMD) w...