Two patients with a history of previous myomectomy came to the centre for infertility evaluation. Both underwent controlled ovarian stimulation followed by ICSI at our centre. Frozen embryo transfer was done hormone replacement therapy protocol where two good quality blastocysts were transferred on day 5. After transfer, urine pregnancy tests positive. But early scans showed pregnancies implant...

With the introduction of intracytoplasmic sperm injection (ICSI), couples with severe male factor infertility have achieved fertilization and clinical pregnancy rates comparable to other in-vitro fertilization (IVF) patients. However, failure of fertilization still occurs in some patients despite the utilization of microsurgical sperm injection techniques. How such fertilization failure after I...

BACKGROUND Since March 2004, only a maximum of three oocytes were allowed to be subjected to ICSI at one time in Italy. A previous study failed to show an impact of this restriction on fresh embryo transfer outcomes. The objective of this study was to compare ICSI outcomes before and after this restriction in patients with nonobstructive azoospermia. METHODS Patients underwent testicular sper...

embryo transfer and its related factors received little clinical attention and had been, until recently, the most inefficient step in in-vitro fertilization (ivf). factors which appear to influence implantation rates are: contamination of the catheter tip with cervical bacteria, stimulation of uterine contractions during the procedure, the type of catheter, ultrasound guidance during the transf...

background: despite of higher pregnancy rate after frozen embryo transfer (fet) which is accepted by the majority of researches, the safety of this method and its effect on neonatal outcome is still under debate. objective: the aim of this study was to evaluate pregnancy and neonatal outcome of fet compare to fresh cycles. materials and methods: in this study,1134 patients using fresh et and 28...

background: we sought to determine the association between factors that affected clinical pregnancy and live birth rates in patients who underwent in vitro fertilization (ivf) and received intracytoplasmic sperm injection (icsi) and/or laser assisted hatching (lah), or neither. materials and methods: in this retrospective cohort study, the records of women who underwent ivf with or without icsi...

BACKGROUND Clinical reproductive centers produce large amounts of surplus poor-quality embryos annually, how to maximize the use of these embryos, and which of them have the potential to develop into blastocyst stage and influencing factors were lack of systematic research. OBJECTIVE To investigate the fate of surplus poor-quality embryos which were cultured to obtain blastocyst, determine th...

Background: Preimplantation genetic aneuploidy screening (PGS) has been performed during the last decade as a way of enhancing embryo selection in patients with an increased incidence of embryonic numerical chromosome abnormalities (advanced maternal age, recurrent miscarriage, and recurrent implantation failure). It has been proposed that the replacement of euploid embryos in these patients wo...

OBJECTIVE To appraise critically the published randomized controlled trials (RCTs) reporting on the effectiveness of cervical mucus removal before embryo transfer. DESIGN Systematic review and meta-analysis of RCTs. SETTING Assisted reproduction technology (ART) units. PATIENT(S) Women undergoing embryo transfer after in vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI). I...

A prospective cohort study has been performed to find out if the administration of an oxytocin antagonist (Atosiban) at the occasion of embryo transfer has an effect on the pregnancy rate in patients with repeated failure of implantation. A total of 52 women with repeated failure of implantation after IVF/ICSI were included in this study. The ongoing pregnancy rate (OPR) in the total group of p...