INTRODUCTION Various optical measurement techniques have been developed for the characterization of surface states during electrochemical processes. Surface plasmon resonance (SPR) spectroscopy has been used in combination with electrochemistry to investigate the electronic structure of metal-electrolyte interfaces [1]. We reported the current efficiency of refractive index changes that occurre...

A highly sensitive electrochemical DNA sensor for detection of the chemotherapeutic drug idarubicin mediated by Methylene blue (MB) has been developed. from fish sperm immobilized at electropolymerized layers Azure B. The incorporation MB into substantially increased sensitivity. concentration range determination cyclic voltammetry was 1 fM to 0.1 nM, with a limit (LOD) 0.3 fM. Electrochemical ...

We present a label-free biosensor based on electrochemical impedance spectroscopy for the detection of proinflammatory cytokine Tumor Necrosis Factor (TNF-α). Secretion of TNF-α has been correlated to the onset of various diseases including rheumatoid arthritis, Crohn’s disease etc. Gold electrodes were patterned on a silicon substrate and self assembled monolayer of dithiobis-succinimidyl prop...

In the present study, an electrochemical DNA sensing strategy for highly sensitivity detection of DNA hybridization was reported based on a gold nanoparticles (AuNPs) / cysteamine (Cys) / poly glutamic acid (PGA) modified electrode. A glassy electrode was first modified with the polymer film by cyclic voltammetry (CV), and then AuNPs were immobilized on the surface of PGA with Cys as a linker, ...

An impedimetric biosensor platform for bio-affinity assays was developed based on real-time, label-free electrochemical detection performed via direct interface to electronic digital data processing. The sensor array consists of 15 gold microelectrode pairs enclosed in three reaction chambers and bio-functionalized with specific DNA probes. The impedance change caused by specific target analyte...

The enzymes immobilization of the is crucially effective factor in biosensor preparation. Metal nanoparticles potentially able to immobilize the enzymes according to unique properties including large surface-to-volume ratio, high surface reaction activity, high catalytic efficiency, and strong adsorption ability. A novel and highly sensitive amperometric glucose biosensor was obtained by using ...

We developed a versatile and highly sensitive biosensor platform. The platform is based on electrochemical-enzymatic redox cycling induced by selective enzyme immobilization on nano-sized carbon interdigitated electrodes (IDEs) decorated with gold nanoparticles (AuNPs). Without resorting to sophisticated nanofabrication technologies, we used batch wafer-level carbon microelectromechanical syste...

Background Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive and memory impairment. It is the most common neurological disease that causes dementia. Soluble amyloid-beta oligomers (AβO) in blood or cerebrospinal fluid (CSF) are the pathogenic biomarker correlated with AD. Methods A simple electrochemical biosensor using graphene oxide/gold nanopar...

Abstract In clinical settings, quickly identifying and detecting bacterial infections is crucial. Current methods for measuring these diseases take a long time are frequently expensive. Hence, biosensor systems may be viable alternative to conventional systems. Electrochemical based on different materials have great potential developing rapid detect pathogens in many areas. They cheaper reliabl...