in a recent editorial for this journal, el-jardali and fadlallah proposed a new framework for knowledge translation (kt) in healthcare. many such frameworks already exist; thus, new entrants to the field must be scrutinized in regard to their unique contributions to advancing understanding and practice. the el-jardali and fadlallah framework focuses on policy-level discussions, a relatively und...

Hemolytic Vibrio cholerae biotype El Tor strains were isolated in the United States in 1973 and 1978 after they had supposedly disappeared worldwide during the 1960s and 1970s. We decided to examine the change in prevalence of hemolytic El Tor strains since the beginning of the seventh pandemic and evaluate the usefulness of hemolytic activity as an epidemiological marker. A total of 48 isolate...

A thermoanalyical study of pure atenolol and a commercial tablets containinf the drug were carried out using thermogravimetric (TG) and differencial scanning calorimetry (DSC) techniques. Nonisothermal method was employed to determine kinetics data of decomposition process. In order to evaluate interaction observed in the commercial tablets, compatibility studies of drug and excipients (microcr...

Feeley and Pittman (Bull. World Health Organ. 28:347, 1963) speculated that a hemolysin (HL) destructive enzyme produced by El Tor vibrio at a late stage of growth lowers the HL titer. We proved the production of an HL-destructive factor (HDF) by strains of classical cholera and El Tor vibrio and established an in vitro method for quantitative titration of HDF. HL was prepared by growing a hemo...

Two pharmacokinetic methods are used primarily to assess systematic bioavailability of orally dosed water-soluble compounds in vivo, but there have been no direct comparisons of the estimates obtained. The "area under the curve" (AUC) method employs a single oral dose of probe compound(s) followed by multiple blood sampling to obtain plasma concentration time curves. Separate injection of probe...

to investigate the effect of different concentrations (0, 0.01% and 0.02%) of salicylic acid (sa) on some quantitative and qualitative characteristics of pomegranate fruit cultivar ‘malase yazdi’ at ripening,2 and 4month ofstorageat5°c, a factorial experiment based on randomized complete block with three replications was conducted. quantitative characteristics including percentage of fruit weig...

Progress in ultrafast science and technology has pushed the temporal resolution to subfemtosecond and attosecond region (Kienberger el at., 2002; Fleischer & Moiseyev, 2006; Corkum & Krausz, 2007; Goulielmakis el at., 2007) and technology exploration in ultrashort pulse generation has made it possible to equip femtosecond lasers that are only a few cycles in duration (Xu el at., 1996; Shirakawa...