The cytosolic epoxide hydrolase (EH-LC) was observed in rhesus monkey liver cytosol, and in both normal and neoplastic human liver. Microsomal epoxide hydrolase (EH-LM) was detected not only in the microsomes of normal and neoplastic human liver and normal rhesus monkey liver, but also in the cytosol of these tissues. No apparent differences were observed between the EH-LM in liver cytosol and ...

EHD1 mediates long-loop recycling of many receptors by forming signaling complexes using its EH domain. We report the design and optimization of cyclic peptides as ligands for the EH domain of EHD1. We demonstrate that the improved affinity from cyclization allows fluorescence-based screening applications for EH domain inhibitors. The cyclic peptide is also unusually well-structured in aqueous ...

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G. C. Lloyd-Roberts, M.Chir., F.R.C.S., Orthopaedic Surgeon, The Hospital for Sick Children, Great Ormond Street, London WC1N 3JH, England. John R. Pincott, MB., B.S., M.R.C.Path., Senior Lecturer in Histopathology at the Institute of Child Health, Guilford Street, London WC1N 1 EH, England. Peter McMeniman, F.R.C.S., 386 Ferguson Road, Norman Park, Brisbane, Australia. I. J. L. Bayley, F.R.C.S...

The bactericidal power of fresh human plasma against Klebsiella pneumoniae and Escherichia coli was extremely sensitive to changes in Eh and pH. At a high Eh (approx. +200 mV) the bacteria were destroyed, but rapid regrowth occurred when the Eh was lowered to approx. -400 mV. Abolition of the bactericidal effect was also produced by adding ferric iron at a high Eh (approx. +200 mV). Lowering th...

Introduction Extracranial vertebral artery aneurysm (EVAA) and extrapleural haematoma (EH) are rare clinical findings most often associated with blunt or penetrating trauma. However, EVAA rupture can be complicated by development of a large EH. Report A 50 year old man underwent an emergency thrombectomy followed by graft reconstruction of an aorto-bi-femoral bypass. The post-operative course...

The UA Indigenous Governance Program is an educational partnership between two units, the Native Nations Institute [4] (NNI) at the Udall Center for Studies in Public Policy [5] and the Indigenous Peoples' Law and Policy Program [6] (IPLP) at the James E. Rogers College of Law [7]. In 2018, its three-week JIT event offers fourteen different courses, ranging from Indigenous Food Sovereignty [8] ...

Most guidelines for making websites accessible for older people have been developed for the Latin alphabet. Currently, there are no web design guidelines for the Thai language or for Thai older people. Our research investigated the effect of font type and size in Thai on skim reading for Thai younger (21-39 years) and older (59-72 years) adults. There were two levels of font types (Conservative...