A case of complete cleft sternum is presented along with the nomenclature of sternal defects. It is recommended that the term ectopia cordis should be applied only to cases in which the heart and thoracic viscera are genuinely ectopic. Surgical correction of complete cleft sternum should be performed in the neonatal period whether the infant is symptomatic or not. Simple closure of the defect, ...

We report about the prenatal diagnosis of pentalogy of Cantrell in the third trimester. In this case sonographic evaluation revealed mild form of ectopia cordis, severe omphalocele, small meningomyelocele, mild hydrocephalus, severe polyhydramnios and allantoic cyst of the umbilical cord. The pregnancy was terminated by a caesarean section at 35 weeks of pregnancy because of severe polyhydramni...

1. Abstract 2. Introduction 3. Methods and Materials 3.1. Generation of the targeting vector 3.2. Electroporation, selection and screening of embryonic stem (ES) cells 3.3. Blastocyst injection and animal breeding 3.4. Isolation of RNA, Quantitative PCR and whole-mount in situ hybridization 3.5. Skeletal X-rays and staining 4. Results 4.1. Generation of Zic3 4.2. Upregulation of Zic3 expression...

A stillborn female with multiple malformations had an unusual ectopia cordis unlike any that have been described insofar as the writer has been able to ascertain. The 39-year-old mother, whose four previous pregnancies resulted in miscarriage, was in good physical condition. Although there was moderate enlargement of her abdomen and no menses for seven months, the mother was not aware that she ...

A male Holstein Friesian calf affected with superior cervical ectopia cordis was examined macroscopically and histologically to assess the severity and elucidate other anomalies. This calf died 10 minutes after birth. The heart was round, weighed 380gm, was enveloped in the pericardium, and situated in the swollen part of the ventrocervical region underneath the skin. Inside the spacious perica...

Ectopia cordis (EC) is a rare malformation due to failure of maturation of the midline mesodermal components of the chest and abdomen. It can be defined as a complete or partial displacement of the heart outside the thoracic cavity. It comprises 0.1% of congenital heart diseases. Common cardiac anomalies associated with EC are ventricular septal defect, atrial septal defect, and tetralogy of Fa...

Dumitrescu A, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-220237 Description We present the video case report (see online supplementary video) of a term newborn with complete sternal cleft and skin defect 2 cm in diameter, without other associated anomaly, including skeletal (figure 1). She was born by elective C-section due to breech presentation. There was no prenatal diagnosis. The baby w...