نتایج جستجو برای: early clinical exposure

تعداد نتایج: 2004987  

2014
Ann Aurell Holmberg Anja Ekdahl Lars Weidolf

During preclinical and early phase clinical studies of drug candidates, exposure to metabolites should be monitored to determine whether safety conclusions drawn from studies in animals can be extrapolated to humans. Metabolites accounting for more than 10% of total exposure to drug-related material (DRM) in humans are of regulatory concern, and for any such metabolites, adequate exposure shoul...

Journal: :The Journal of nervous and mental disease 2006
Gemma L Gladstone Gordon B Parker Gin S Malhi

There is little empirical research examining the historical and clinical correlates of exposure to childhood bullying in adult clinical subjects. Using structured clinical assessments, the authors studied a group of adult males and females presenting to an outpatient depression clinic, to examine the childhood risk factors and the distinguishing comorbid features associated with those reporting...

Journal: :Occupational and Environmental Medicine 1945

Journal: :The International journal of oral & maxillofacial implants 2001
H Tal Z Artzi O Moses C E Nemcovsky A Kozlovsky

Spontaneous early exposure of submerged implants during the osseointegration healing phase may be a harmful factor that results in early crestal bone loss around the implants. The objective of this study was to assess the effect of spontaneous early exposure on crestal bone loss around submerged implants, with special attention given to the relationship between the degree of exposure and the am...

ژورنال: پرستاری کودکان 2021

Introduction: In Modern technology, using mobile phones is the most exposed to waves in the world. As far, public concern has been rising regarding exposure to phone waves, especially in critical periods such as intrauterine life and early childhood. This study aimed to conduct a systematic review of literature have investigated the relationship between exposure to radiofrequency waves during p...

Journal: :Clinical and Translational Allergy 2011

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