OBJECTIVE The molecular mechanisms regulating vascular permeability are only now being elucidated. The junctional adhesion molecule (JAM) JAM-C has been linked to the induction of vascular permeability. We sought to understand the mechanism whereby JAM-C may disrupt junctional integrity in endothelial cells (ECs). METHODS AND RESULTS We show here that JAM-C alters permeability through modulat...

This article focuses on the mathematical problem of reconstructing dynamic permeability K(ω) of two-phase composites from data at different frequencies, utilizing the analytic structure of K(ω). To numerically simulate the data by solving the unsteady Stokes equations in the 3D domain reconstructed from μ-CT scans of the composites, the issue of segmentation is also addressed in this paper and ...

Daqing Oilfield is rich in low permeability reservoirs. In order to fully understand the development dynamics of ultra-low reservoirs, this paper takes as an example and studies productivity fractured horizontal Wells by numerical simulation method. The results show that decreases exponentially with decrease formation permeability. well increases fracture length spacing. With increase coefficie...

Hydrogen is a clean fuel which has the potential to drastically decarbonize energy supply chain. However, hydrogen storage currently key challenge; one solution this problem geo-storage, with very large quantities of H2 can be stored economically. Possible target formations are deep coal seams, and permeability parameter determines how fast injected withdrawn again. it well known that gas injec...

Abstract With the continuous increase of wind power permeability, dynamic behavior system also changes, which has a great impact on setting low-frequency load-shedding scheme. The original scheme no good adaptability to high-permeability power. So, this article analyzes principles turbines in grid frequency control. This paper expounds principle strategy configuration. Connecting with actual op...

Compromised blood-spinal cord barrier (BSCB) is a factor in the outcome following traumatic spinal cord injury (SCI). Vascular endothelial growth factor (VEGF) is a potent stimulator of angiogenesis and vascular permeability. The role of VEGF in SCI is controversial. Relatively little is known about the spatial and temporal changes in the BSCB permeability following administration of VEGF in ex...