A series of novel aliphatic polyesters with azido functional groups were synthesized via the direct lipase-catalyzed polycondensation of dialkyl diester, diol and 2-azido-1,3-propanediol (azido glycerol) using immobilized lipase B from Candida antarctica (CALB). The effects of polymerization conditions including reaction time, temperature, enzyme amount, substrates and monomer feed ratio on the...

Metabolic alterations are known to occur with oncogenesis and tumor progression. During malignant transformation, the metabolism of cells and tissues is altered. Cancer metabolism can be studied using advanced technologies that detect both metabolites and metabolic activities. Identification, characterization, and quantification of metabolites (metabolomics) are important for metabolic analysis...

Abstract. The review describes the application of nuclear magnetic resonance (NMR) spectroscopy to study kinetics folding, refolding and aggregation proteins, RNA DNA. Time-resolved NMR experiments can be conducted in a reversible or an irreversible manner. In particular, folding pose large requirements for (i) signal-to-noise due time limitations (ii) synchronising steps. Thus, this contributi...

The assembly formation of Zn cluster compounds comprising pyridinealcohol ligands is described and their solution and solid state features have been determined using NMR spectroscopy and X-ray diffraction. The di-Zn complex 5 and tetra-Zn complex 7 may serve as accessible structural models for the active site of various multinuclear Zn-containing metalloenzymes. Their phosphoester cleavage acti...

ssNMR (solid-state NMR) spectroscopy provides increasing possibilities to study the structural and dynamic aspects of biological membranes. Here, we review recent ssNMR experiments that are based on MAS (magic angle spinning) and that provide insight into the structure and dynamics of membrane systems at the atomic level. Such methods can be used to study membrane architecture, domain formation...

Nuclear Magnetic Resonance (NMR) is a powerful technique to probe the local environment of atoms bearing nuclear spin. Interfaces in rechargeable battery, within multi-component electrode or electrolytes between electrodes and electrolyte, are key its function lifetime. NMR spectroscopy solid phases battery participate understanding processes at these interfaces. The solid-state community still...

Microfluidic stripline NMR technology not only allows for NMR experiments to be performed on small sample volumes in the submicroliter range, but also experiments can easily be performed in continuous flow because of the stripline’s favorable geometry. In this study we demonstrate the possibility of dual-channel operation of a microfluidic stripline NMR setup showing oneand twodimensional H, C ...