Background: Crohn's disease (CD) is a type of inflammatory bowel disease (IBD) which despite the unknown details is generally related to genetic, immune system, and environmental factors. In this study, we identify transcriptional signatures in patients with CD and then explain the potential molecular mechanisms in inflamed and non-inflamed intestinal mucosa in these patients. Materials and Me...

We propose a new method for creating an optimal coherence in a two-level system (TLS) based on adiabatic following. Optimal coherence is achieved by choosing the time-dependent phase of the pulse that provides vanishing field-TLS detuning dðtÞ at central time when the pulse amplitude reaches maximum. For example, dðtÞ 1⁄4 d0ð1 expððt t0Þ=s0ÞÞ for t 6 t0 and d 1⁄4 0 for t > t0. The pulse envelop...

There are various types of lasers available for hair reduction, but the choice of an ideal laser for ethnic skin has its own limitations. The choice of the right laser for the right skin type is very important. Before starting with the laser therapy, it is important to assess the skin type, the fluence, the pulse duration and the type of laser to be used.

Objective(s):Fumonisins are a group of toxic and carcinogenic mycotoxins, which contaminate the grains and their products. The aim of this study was to examine the apoptotic and proliferative activity of mouse gastric mucosa following administration of fumonisin B1 (FB1).    Materials and Methods: Twenty-nine female mice divided into treatment (n=15) and control (n=14) groups. The treatment gro...

background :the diagnosis of malignant and potentially malignant epithelial lesions of the oral mucosa cannot be based solely on clinical findings. therefore, histologic evaluation of a representative biopsy specimen is necessary. however the site for the biopsy is always a subjective choice that sometimes raises doubts about its representativeness. colposcopy, a well-known gynecological diagno...

BACKGROUND AND AIM: Epidemiological studies have established a wide variation in the prevalence of oral lesions in different population. Officially oral mucosa diseases can occur in 25-50% of cases, depending on the population to which the survey was conducted. We examined the relationship between oral mucosal lesions, tongue pH level, gingivitis, oral hygiene, and oral health behaviors in stud...

in order to formulate an efficient and durable mucoadhesive drug delivery system, careful consideration of formulation-related parameters is critical. this study was conducted to investigate the effect of the presence of various types and concentrations of surfactants within or outside carbopol 934 (c934) as well as hydroxypropylmethyl cellulose (hpmc) solid compacts, on their duration of mucoa...

background: oral contraceptive pills are among the most popular contraceptive methods, but the fear of cancer and cardiovascular disease overshadows its continuous use among women. this study aimed to define the association between consumption patterns of combined oral contraceptives among women with breast cancer. materials and methods: this is an analytical case–control study conducted on 175...

Background and aim: Increased rate of micronucleus in buccal mucosa cells and its correlation with carcinogenesis is worth consideration. Recently, occupation in dental laboratories has been proposed as a predisposing factor. Therefore, the present study aimed to evaluate the effect of occupational exposure on buccal mucosa cells of dental laboratory technicians. Materials and methods: This ...

introduction: leukoplakia is the most common precancerous lesion of the oral mucosa and may range microscopically form benign hyperkeratosis to invasive squamous cell carcinoma. p53 is a tumor suppressor protein; whereas, proliferative cell nuclear antigen (pcna) is a proliferative marker. the aim of this study was to evaluate the immunohistochemical expressions of p53 and pcna in oral leukopla...