AIM: To report ocular changes in rabbits after the implementation of three different induction methods to create dry eye (DE) conditions and provides evidence DE-related disease evolution. METHODS: Experimental were divided into 3 models. The first model used involved triple injection complete Freund’s adjuvant, 50 µL each, also called meibomian gland dysfunction (MGD) model. In second model, D...

Background: Post- Laser- assisted in situ keratomileusis (LASIK) dry eye is one of the most common postoperative eyes after ophthalmic surgeries. Clinically, patients have positive vital staining ocular surface, decreased tear breakup times, reduced corneal sensitivity, and visual acuity. In majority patients, symptoms last about month, but some can experience these for more than a year. Case p...