A. For f > g ∈ ω let c∀f ,g be the minimal number of uniform trees with g-splitting needed to ∀-cover the uniform tree with f -splitting. c∃f ,g is the dual notion for the ∃ cover. Assuming CH and given א1 many (sufficiently different) pairs ( f2 , g2 ) and cardinals κ2 such that κ0 2 = κ2 , we construct a partial order forcing that c∃f2 ,g2 = c ∀ f2 ,g2 = κ2 . For this, we introduce a c...

This paper considers the cycle covering of complete graphs motivated by the design of survivable WDM networks, where the requests are routed on sub-networks which are protected independently from each other. The problem can be stated as follows : for a given graph G, find a cycle covering of the edge set of Kn, where V (Kn) = V (G), such that each cycle in the covering satisfies the disjoint ro...

I f a picture paints a thousand words, the text generated by cryoelectron tomography (cryo-ET) could fi ll volumes. High resolution 3D reconstructions of fl agellar axonemes generated using cryo-ET are shaping our understanding of how structure relates to function, a point exemplifi ed by a new study which assigns a molecular identity to a formerly elusive ciliary structural feature—the nexin l...

Patients who undergo autologous hematopoietic stem cell transplantation (aHCT) for treatment of a relapsed or refractory lymphoma are at risk of developing therapy related- myelodysplasia/acute myeloid leukemia (t-MDS/AML). Part of the risk likely resides in inherent interindividual differences in their DNA repair capacity (DRC), which is thought to influence the effect chemotherapeutic treatme...

We investigated the genetic diversity of measles virus (MV) in Nigeria (2004-2005) and the Democratic Republic of the Congo (DRC) (2002-2006). Genotype B3 strains circulating in Kinshasa, DRC, in 2002-2003 were fully replaced by genotype B2 in 2004 at the end of the second Congo war. In Nigeria (2004-2005), two genetic clusters of genotype B3, both of which were most closely related to 1 varian...

Both reduced DNA repair capacity (DRC) and folate deficiency are associated with increased cancer risk. Furthermore, folate is involved in DNA repair through de novo DNA synthesis and methylation. To determine whether low dietary folate intake is associated with low cellular DRC in humans, we assessed total dietary folate intake using a food frequency questionnaire in 559 non-Hispanic white can...

Breast cancer (BC) is a heterogeneous disease which many studies have classified in at least four molecular subtypes: Luminal A, Luminal B, HER2-Enriched, and Basal-like (including triple-negative breast cancer, TNBC). These subtypes provide information to stratify patients for better prognostic predictions and treatment selection. Individuals vary in their sensitivities to carcinogens due to d...