The aim of this study was to compare the two types of drug-eluting stents with histological analysis in porcine coronary restenosis model. Pigs were randomized into two groups in which the coronary arteries (12 pigs, 12 coronaries in each group) had either biolimus-eluting stent with biodegradable polymer (BPS) or sirolimus-eluting stent with durable polymer (DPS). Radiological analysis was per...

OBJECTIVE This study investigates isolated effects of vection and optokinetic nystagmus (OKN) on visually induced motion sickness (VIMS) provoked by rotating optokinetic drum patterns. BACKGROUND VIMS was the subject of recent standardization activities, but the effects of OKN have not been studied in the absence ofvection. METHOD Experiment 1 suppressed OKN by eye fixation and examined VIM...

Synaptic vesicle (SV) release is spatially and temporally regulated by a network of proteins that form the presynaptic active zone (AZ). The hallmark of most AZs is an electron-dense projection (DP) surrounded by SVs. Despite their importance for our understanding of triggered SV release, high-resolution analyses of DP structures are limited. Using electron microscopy, we show that DPs at Caeno...

AIMS This research sought (a) to investigate the similarities and differences in how pharmaceutical services are provided by community pharmacies (CPs) and dispensing doctor practices (DPs) and (b) to identify the issues relevant to determining the quality of pharmaceutical services in these settings. BACKGROUND UK pharmaceutical services, including dispensing prescriptions and public health ...

Since the adoption of Abney’s (1987) influential proposal that noun phrases are (at most) DPs, the hypothesis that not all noun phrases in all languages are DPs has been widely debated. A particularly interesting case in this respect is presented by Slavic languages lacking overt articles such as Russian or Serbo-Croatian: are noun phrases in such languages ever DPs, always DPs, or sometimes DP...

Currently valid itch intensity scales, such as the visual analogue scale (VAS), are indispensable, but they can be influenced by the patient's overall health status. The aim of this study was to evaluate the reliability and validity of the Dynamic Pruritus Score (DPS), a new instrument comparing reduction in current pruritus with a defined earlier time-point. Eighty-one randomly selected adults...

Resistance to phagocyte-derived reactive oxygen species is essential for Salmonella enterica serovar Typhimurium pathogenesis. Salmonella can enhance its resistance to oxidants through the induction of specific genetic pathways controlled by SoxRS, OxyR, sigma(S), sigma(E), SlyA, and RecA. These regulons can be found in a wide variety of pathogenic and environmental bacteria, suggesting that ev...

Finding motifs and the corresponding binding sites is a critical and challenging problem in studying the process of gene expression. String and matrix representations are two popular models to represent a motif. However, both representations share an important weakness by assuming that the occurrence of a nucleotide in a binding site is independent of other nucleotides. More complicated represe...

OBJECTIVE To evaluate the effects of functional electrical stimulation (FES) to ankle dorsiflexor (DF) and ankle plantarflexor (PF) on kinematic and kinetic parameters of hemiplegic gait. METHODS Fourteen post-stroke hemiplegic patients were considered in this study. Electrical stimulation was delivered to ankle DF during the swing phase and ankle PF during the stance phase via single foot sw...

This paper deals with the complexity of the decomposition of a digital surface into digital plane segments (DPS for short). We prove that the decision problem (does there exist a decomposition with less than λ DPS ?) is NP-complete, and thus that the optimisation problem (finding the minimum number of DPS) is NP-hard. The proof is based on a polynomial reduction of any instance of the well-know...