The standard management of locally advanced rectal cancer (LARC) is neoadjuvant chemoradiotherapy (CRT) combined with carcinologic resection. This approach has resulted in down-sizing and down-staging the tumour. A major pathological response (ypT0-1 N0) associated better survival, less local recurrence, distant failure. We aimed to describe clinicopathological features key determinants outcome...

Intrahepatic cholangiocarcinoma (ICC) was differentiated from hepatocellular carcinoma, as defined in the American Joint Committee on Cancer (AJCC) 6th edition staging manual, using the revised staging system described in the AJCC 7th edition staging manual. This study was conducted to analyze the application of the AJCC 6th and 7th edition staging classifications and to evaluate a modified sta...

Background & Objective: Malignant melanoma is the fatal cutaneous neoplasm which is curable by the early diagnosis. The expression of occludin protein which is an integral membrane protein is altered in an epithelial-to-mesenchymal transition. Although, recent studies provide sufficient evidence supporting the functional importance of occludin in cancer, the prognostic signific...

Accurate staging of esophageal cancer is very important to achieving optimal treatment outcomes. The AJCC (American Joint Committee on Cancer) first published TNM esophageal cancer staging recommendations in the first edition of their staging manual in 1977. Thereafter, the staging of esophageal cancer was changed many times over the years. This article reviews the current status of staging of ...

OBJECTIVES Combined androgen blockade (CAB) uning LH-RH agonist and flutamide has been performed as neoadjuvant therapy for T 2, 3 prostate cancers (CaP). The histological effects of neoadjuvant CAB therapy and influential factors were investigated. METHODS Materials were 20 CaP cases which were underwent radical prostatectomy (RP) after neoadjuvant CAB therapy. All cases were diagnosed by ec...

We describe a patient with newly diagnosed limy cancer. Staging was performed with CT and mediastinoscopy. FDG PET scan was performed and confirmed increased metabolic activity in the primary tumor as well as the hilar lymph node. Seven months after initial presentation, the patient was found to have two lytic lesions in the pelvis on plain radiograph. Hone scan was negative but PET demon...

Water tank is used extensively for storing water, inflammable liquids and other chemicals. Generally, to provide water at large, tank is supported on frame or shaft (a vertical cylindrical shell). The staging with a single row of columns placed straight (vertical) along the periphery of circle or shaft, are generally adopted for elevated water tanks to support the tank container. Apart from ver...