The external quality assessment of 24-locus mycobacterial interspersed repetitive-unit–variable-number tandem-repeat (MIRU-VNTR) genotyping by de Beer et al. reveals issues with its international performance (5). Detailed analysis of the data was confounded by the complexity of the participants. The five genotyping laboratories in Canada and the United States participating in this study use sim...

One of the most fascinating questions in evolutionary biology is understanding how novelties such as new organs or novel body plans arise. Answering this question is all the more challenging as obvious predecessors cannot always be identified in the incomplete fossil record. Evolutionary developmental (evo-devo) studies address this issue by examining how developmental mechanisms have evolved o...

In Part I of an article on "Cultural Action for Freedom," Freire advocates a theory and practice of the adult literacy process based upon authentic dialogue between teachers and learners. Becoming literate is truly an act of knowing, through which a person is able to look critically at the world and to reflect and act upon it. In this article, Part I of Cultural Action for Freedom, Paulo Freire...

Computer music tends to be the domain of musicians, electrical engineers, mathematicians, and physicists. Today, only CS1-level knowledge is necessary to do a serious review and exploration of computer music, as the algorithms have become more well understood (and thus easier to explain), and Moore’s Law makes even inefficient algorithms successful. A serious impediment, however, has been the l...

In the past months, systematically higher levels of severe COVID-19 illness and death among individuals belonging to migrant or ethnic minority groups have been reported in several countries, including USA, UK, Sweden, Brazil, Spain South Africa. particular, racialized populations tend less access testing, rates disease, mortality worse sequalae when they survive infection [1Holmes Jr., L. Enwe...

Complex datasets provide opportunities for discoveries beyond their initial scope. Effective and rapid data sharing management practices are crucial to realize this potential; however, they harder implement than post-publication access. Here, we introduce the concept of a “data trust” maximize value large datasets. With advent new technologies an appreciation systems-level analyses, there growi...

Hepatology, Medicine and Policy (HMAP), a new open-access peer-reviewed journal, is making its debut at a time when the hepatitis field is seeing great progress but still has far to go. The World Health Organization and many countries have shown increasing interest in viral hepatitis in recent years, helping to foster a stronger response to this group of diseases. Meanwhile, alcohol-associated ...

In times where computer-assisted representations dominate the “market” of visual simulation, the major strongholds of simulation in true size in conveying (artificial) light configurations have been observed. Though light cannot be “touched” due to its material absence the human eye reacts extremely sensitively to differing constellations. In matters of seconds differences are perceived and cla...

What are the minimal requirements to tell a story by means of some digital game? What are minimal short stories worth to be told? How to establish the minimal preliminaries of interactive storytelling? What do we expect of computerized counterparts that are worth to be mentioned in a story humans experience when playing a digital game? The authors have designed, implemented and experimentally u...

The story of human history was changed forever in 1863 with William King's proposal that we had not always been the sole members Homo genus. Yet, more than 150 years after neanderthalensis first named and then summarized pages Anthropological Review, man responsible for this revolutionary announcement is poorly known field palaeoanthropology today. Following sesquicentennial anniversary seminal...